KEGG   DRUG: D04788Help
Entry
D04788                      Drug                                   

Name
Lubazodone hydrochloride (USAN)
Formula
C14H18FNO2. HCl
Exact mass
287.1088
Mol weight
287.7576
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant [selective serotonine (5-HT) reuptake inhibitor and 5-HT2A antagonist]
Comment
Serotonin reuptake inhibitor (SRI)
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor
     Lubazodone
      D04788  Lubazodone hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
161178-10-5
PubChem: 
LigandBox: 
KCF data Show

ATOM        19
            1   C1y C    40.9536  -28.1100
            2   O2x O    39.7219  -28.8216
            3   C1x C    39.7223  -30.2197
            4   C1x C    40.9332  -30.9184
            5   N1x N    42.1650  -30.2068
            6   C1x C    42.1645  -28.8087
            7   C8x C    38.5487  -22.5180
            8   C8x C    38.5487  -23.9161
            9   C8y C    39.7594  -24.6151
            10  C8y C    40.9703  -23.9161
            11  C8y C    40.9703  -22.5180
            12  C8y C    39.7594  -21.8190
            13  C1x C    42.2999  -24.3481
            14  C1x C    43.1217  -23.2171
            15  C1x C    42.2999  -22.0860
            16  O2a O    39.7594  -26.0130
            17  X   F    39.7594  -20.4211
            18  C1b C    40.9534  -26.7025
            19  X   Cl   44.7701  -26.9919
BOND        20
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     7   8 2
            8     8   9 1
            9     9  10 2
            10   10  11 1
            11   11  12 2
            12    7  12 1
            13   10  13 1
            14   13  14 1
            15   14  15 1
            16   11  15 1
            17    9  16 1
            18   12  17 1
            19   16  18 1
            20    1  18 1 #Down

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