KEGG   DRUG: Lutropin alfaHelp
Entry
D04824                      Drug                                   

Name
Lutropin alfa (USAN/INN);
Luveris (TN)
Sequence
(alpha-subunit) APDVQDCPEC TLQENPFFSQ PGAPILQCMG CCFSRAYPTP
LRSKKTMLVQ KNVTSESTCC VAKSYNRVTV MGGFKVENHT ACHCSTCYYH KS
(beta-subunit) SREPLRPWCH PINAILAVEK EGCPVCITVN TTICAGYCPT
MMRVLQAVLP PLPQVVCTYR DVRFESIRLP GCPRGVDPVV SFPVALSCRC GPCRRSTSDC
GGPKDHPLTC DHPQLSGLLF L
  Type
Peptide
Remark
ATC code: G03GA07
Efficacy
Ovulation inducing agent, Luteinizing hormone/choriogonadotropin receptor agonist
Comment
Luteinizing hormone (human alfa-subunit reduced [DR:D04429]), complex with Luteinizing hormone (human beta-subunit reduced), glycoform alfa
Treatment of chronic anovulation due to hypogonadotropic hypogonadism
Target
LHCGR [HSA:3973] [KO:K04248]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
   G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
    G03GA Gonadotropins
     G03GA07 Lutropin alfa
      D04824  Lutropin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Lutropin-choriogonadotropic hormone
    luteinizing hormone/choriogonadotropin receptor
     Lutropin alfa
      D04824  Lutropin alfa (USAN/INN)
New drug approvals in Europe [br08329.html]
 European public assessment reports (EPAR) authorised medicine
  D04824
BRITE hierarchy
Other DBs
CAS: 152923-57-4
PubChem: 47206610
DrugBank: DB00044

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