| Entry |
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| Name |
Lutropin alfa (USAN/INN);
Luveris (TN)
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| Sequence |
(alpha-subunit) APDVQDCPEC TLQENPFFSQ PGAPILQCMG CCFSRAYPTP
LRSKKTMLVQ KNVTSESTCC VAKSYNRVTV MGGFKVENHT ACHCSTCYYH KS
(beta-subunit) SREPLRPWCH PINAILAVEK EGCPVCITVN TTICAGYCPT
MMRVLQAVLP PLPQVVCTYR DVRFESIRLP GCPRGVDPVV SFPVALSCRC GPCRRSTSDC
GGPKDHPLTC DHPQLSGLLF L |
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| Type |
Peptide |
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| Activity |
Treatment of chronic anovulation due to hypogonadotropic hypogonadism
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| Remark |
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| Comment |
Luteinizing hormone (human alfa-subunit reduced [DR: D04429]), complex with Luteinizing hormone (human beta-subunit reduced), glycoform alfa
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| Target |
luteinizing hormone/choriogonadotropin receptor agonist [HSA: 3973] [KO: K04248] |
|---|
| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03G GONADOTROPINS AND OTHER OVULATION STIMULANTS
G03GA Gonadotropins
G03GA07 Lutropin alfa
D04824 Lutropin alfa (USAN/INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Lutropin-choriogonadotropic hormone
luteinizing hormone/choriogonadotropin receptor
Lutropin alfa
D04824 Lutropin alfa (USAN/INN)
 |
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| Other DBs |
CAS: 152923-57-4 PubChem: DrugBank: |
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