KEGG   DRUG: D04870Help
Entry
D04870                      Drug                                   

Name
Mecasermin rinfabate (USAN/INN);
Iplex (TN)
Formula
C1231H1967N371O384S20
Exact mass
28731.0209
Mol weight
28749.345
Sequence
(IGF-I) GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR
SCDLRRLEMY CAPLKPAKSA
(IGFBP-3) GASSAGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE
GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA
SESEEDRSAG SVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT
QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR
KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK
  Type
Peptide
Activity
Antidiabetic
Remark
ATC code: 
Drug group: 
Target
insulin-like growth factor 1 receptor agonist [HSA:3480] [KO:K05087]
  Pathway
hsa04114  Oocyte meiosis
hsa04144  Endocytosis
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04914  Progesterone-mediated oocyte maturation  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
  H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
   H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
    H01AC Somatropin and somatropin agonists
     H01AC05 Mecasermin rinfabate
      D04870  Mecasermin rinfabate (USAN/INN)
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Pituitary)
  Mecasermin
   D04870  Mecasermin rinfabate (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Receptor tyrosine kinase
   RTK class II (Insulin receptor family)
    insulin-like growth factor 1 receptor
     Mecasermin
      D04870  Mecasermin rinfabate (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
478166-15-3
PubChem: 
DrugBank: 

» Japanese version   » Back

DBGET integrated database retrieval system