| Entry |
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| Name |
Mecasermin rinfabate (USAN/INN);
Iplex (TN)
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| Formula |
C1231H1967N371O384S20
|
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| Exact mass |
28731.0209
|
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| Mol weight |
28749.345
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| Sequence |
(IGF-I) GPETLCGAEL VDALQFVCGD RGFYFNKPTG YGSSSRRAPQ TGIVDECCFR
SCDLRRLEMY CAPLKPAKSA
(IGFBP-3) GASSAGLGPV VRCEPCDARA LAQCAPPPAV CAELVREPGC GCCLTCALSE
GQPCGIYTER CGSGLRCQPS PDEARPLQAL LDGRGLCVNA SAVSRLRAYL LPAPPAPGNA
SESEEDRSAG SVESPSVSST HRVSDPKFHP LHSKIIIIKK GHAKDSQRYK VDYESQSTDT
QNFSSESKRE TEYGPCRREM EDTLNHLKFL NVLSPRGVHI PNCDKKGFYK KKQCRPSKGR
KRGFCWCVDK YGQPLPGYTT KGKEDVHCYS MQSK |
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| Type |
Peptide |
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| Activity |
Antidiabetic
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| Remark |
|
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| Target |
insulin-like growth factor 1 receptor agonist [HSA: 3480] [KO: K05087] |
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| Pathway |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H01 PITUITARY AND HYPOTHALAMIC HORMONES AND ANALOGUES
H01A ANTERIOR PITUITARY LOBE HORMONES AND ANALOGUES
H01AC Somatropin and somatropin agonists
H01AC05 Mecasermin rinfabate
D04870 Mecasermin rinfabate (USAN/INN)
USP drug classification [BR:br08302]
Hormonal Agents
Hormonal Agents, Stimulant / Replacement / Modifying (Pituitary)
Insulin-like Growth Factor Analogs
Mecasermin
D04870 Mecasermin rinfabate (USAN/INN)
Target-based classification of drugs [BR:br08310]
Cytokine receptors
Receptor tyrosine kinase
RTK class II (Insulin receptor family)
insulin-like growth factor 1 receptor [HSA:3480] [KO:K05087]
Mecasermin rinfabate [ATC:H01AC05]
D04870 Mecasermin rinfabate (USAN/INN)
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| Other DBs |
CAS: 478166-15-3 PubChem: DrugBank: |
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