KEGG   DRUG: D04972Help
Entry
D04972                      Drug                                   

Name
Methacycline (USAN);
Metacycline (INN)
Formula
C22H22N2O8
Exact mass
442.1376
Mol weight
442.4187
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
Same as: 
ATC code: 
Drug group: 
Target
16S rRNA of 30S ribosomal subunit, protein synthesis inhibitor [KO:K01977]
  Pathway
ko03010  Ribosome  
 
Interaction
Drug interaction
Structure map
Tetracyclines
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01A TETRACYCLINES
    J01AA Tetracyclines
     J01AA05 Metacycline
      D04972  Methacycline (USAN); Metacycline (INN)
Antiinfectives [BR:br08307]
 Antibacterials
  Protein biosynthesis inhibitor
   16S rRNA of 30S ribosomal subunit inhibitor
    Tetracyclines
     Metacycline
      D04972  Methacycline (USAN); Metacycline (INN)
BRITE hierarchy
Other DBs
CAS: 
914-00-1
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C8x C    11.1300   -9.3800
            2   C8x C    11.1300  -10.7800
            3   C8y C    12.3424  -11.4800
            4   C8y C    13.5549  -10.7800
            5   C8y C    13.5549   -9.3800
            6   C8x C    12.3424   -8.6800
            7   C5x C    14.7673  -11.4800
            8   C2y C    15.9797  -10.7800
            9   C1y C    15.9797   -9.3800
            10  C2y C    14.7673   -8.6800
            11  C2y C    17.1922  -11.4800
            12  C1z C    18.4046  -10.7800
            13  C1y C    18.4046   -9.3800
            14  C1y C    17.1922   -8.6800
            15  C5x C    19.6170  -11.4800
            16  C2y C    20.8295  -10.7800
            17  C2y C    20.8295   -9.3800
            18  C1y C    19.6170   -8.6800
            19  C2a C    14.7673   -7.2800
            20  O5x O    14.7673  -12.8800
            21  O5x O    19.6170  -12.8799
            22  O1a O    12.3424  -12.8798
            23  O1a O    17.1922  -12.8797
            24  C5a C    22.0646  -11.4934
            25  N1a N    23.2719  -10.7966
            26  O5a O    22.0642  -12.8799
            27  O1a O    22.0646   -8.6666
            28  O1a O    17.1922   -7.0703
            29  N1c N    19.6170   -6.5100
            30  O1a O    18.4046  -12.1800
            31  C1a C    20.8166   -5.8173
            32  C1a C    18.3919   -5.8026
BOND        35
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16    9  14 1
            17   12  15 1
            18   15  16 1
            19   16  17 2
            20   17  18 1
            21   13  18 1
            22   10  19 2
            23    7  20 2
            24   15  21 2
            25    3  22 1
            26   11  23 1
            27   16  24 1
            28   24  25 1
            29   24  26 2
            30   17  27 1
            31   14  28 1 #Down
            32   18  29 1 #Down
            33   12  30 1 #Down
            34   29  31 1
            35   29  32 1

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