KEGG   DRUG: D05035Help
Entry
D05035                      Drug                                   

Name
Milameline hydrochloride (USAN)
Formula
C8H14N2O. HCl
Exact mass
190.0873
Mol weight
190.6705
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidementia [partial muscarinic agonist]
Target
muscarinic cholinergic receptor agonist [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse
hsa04970  Salivary secretion
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Milameline
      D05035  Milameline hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
139886-04-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        12
            1   N1y N    16.5200  -16.5200
            2   C1x C    16.5200  -17.9200
            3   C1x C    17.7324  -18.6200
            4   C2x C    18.9449  -17.9200
            5   C2y C    18.9449  -16.5200
            6   C1x C    17.7324  -15.8200
            7   C2b C    20.1760  -15.8090
            8   C1a C    15.3076  -15.8200
            9   N2b N    21.3812  -16.5047
            10  O2a O    22.5635  -15.8219
            11  C1a C    23.7575  -16.5112
            12  X   Cl   24.5000  -18.6900
BOND        11
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     5   7 1
            8     1   8 1
            9     7   9 2
            10    9  10 1
            11   10  11 1

» Japanese version   » Back

DBGET integrated database retrieval system