KEGG   DRUG: D05036Help
Entry
D05036                      Drug                                   

Name
Milodistim (USAN/INN);
Pixykine (TN)
Formula
C1336H2116N362O410S13
Exact mass
30207.2225
Mol weight
30226.1206
Sequence
APARSPSPST QPWEHVNAIQ EALRLLDLSR DTAAEMNEEV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQEGGG GSGGGGGSAP MTQTTPLKTS WVDCSNMIDE IITHLKQPPL PLLDFNNLNG
EDQDILMENN LRRPNLEAFN RAVKSLQDAS AIESILKNLL PCLPLATAAP TRHPIHIKDG
DWNEFRRKLT FYLKTLENAQ AQQTTLSLAI F
  Type
Peptide
Activity
Hematopoietic stimulant;
Antineutropenic
Comment
A recombinant fusion protein (GM-CSF [HSA:1440] [KO:K05423] /IL3 [HSA:3562] [KO:K04736])
Target
granulocyte colony stimulating factor (G-CSF) receptor agonist [HSA:1441] [KO:K05061];
interleukin-3 (IL-3) receptor agonist [HSA:3563] [KO:K04737]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway
hsa04640  Hematopoietic cell lineage  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   granulocyte colony stimulating factor (G-CSF) receptor
    Milodistim
     D05036  Milodistim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
137463-76-4
PubChem: 

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