KEGG   DRUG: Neramexane mesylateHelp
Entry
D05145                      Drug                                   

Name
Neramexane mesylate (USAN)
Formula
C11H23N. CH4SO3
Exact mass
265.1712
Mol weight
265.4127
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Efficacy
Antidepressant, Dementia therapeutic agent, NMDA receptor antagonist
Comment
Treatment of depression, Alzheimer's disease, and pain
Target
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Ligand-gated ion channels
   Glutamate (ionotropic), NMDA
    GRIN (NMDAR)
     D05145  Neramexane mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 457068-92-7
PubChem: 47206869
ChEMBL: CHEMBL2106798
LigandBox: D05145
KCF data Show

ATOM        17
            1   C1z C     8.5400  -14.4200
            2   C1x C     8.5400  -15.8200
            3   C1z C     9.7524  -16.5200
            4   C1x C    10.9649  -15.8200
            5   C1z C    10.9649  -14.4200
            6   C1x C     9.7524  -13.7200
            7   C1a C     8.7625  -17.5099
            8   C1a C    10.7424  -17.5099
            9   N1a N    12.1960  -13.7090
            10  C1a C     7.3276  -13.7200
            11  C1a C     7.3276  -15.1200
            12  C1a C    12.1961  -15.1309
            13  O1d O    17.3605  -14.8060
            14  S4a S    17.3605  -16.2024
            15  C1a C    15.9642  -16.2024
            16  O1d O    18.7569  -16.2024
            17  O1d O    17.3605  -17.5987
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     3   7 1
            8     3   8 1
            9     5   9 1
            10    1  10 1
            11    1  11 1
            12    5  12 1
            13   13  14 2
            14   14  15 1
            15   14  16 1
            16   14  17 2

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