KEGG   DRUG: D05145Help
Entry
D05145                      Drug                                   

Name
Neramexane mesylate (USAN)
Formula
C11H23N. CH4SO3
Exact mass
265.1712
Mol weight
265.4127
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of depression, Alzheimer's disease, and pain
Target
N-methyl-D-aspartate receptor antagonist [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04720  Long-term potentiation
hsa04724  Glutamatergic synapse  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Neramexane
      D05145  Neramexane mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
457068-92-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        17
            1   C1z C     8.5400  -14.4200
            2   C1x C     8.5400  -15.8200
            3   C1z C     9.7524  -16.5200
            4   C1x C    10.9649  -15.8200
            5   C1z C    10.9649  -14.4200
            6   C1x C     9.7524  -13.7200
            7   C1a C     8.7625  -17.5099
            8   C1a C    10.7424  -17.5099
            9   N1a N    12.1960  -13.7090
            10  C1a C     7.3276  -13.7200
            11  C1a C     7.3276  -15.1200
            12  C1a C    12.1961  -15.1309
            13  O1d O    17.3605  -14.8060
            14  S4a S    17.3605  -16.2024
            15  C1a C    15.9642  -16.2024
            16  O1d O    18.7569  -16.2024
            17  O1d O    17.3605  -17.5987
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     3   7 1
            8     3   8 1
            9     5   9 1
            10    1  10 1
            11    1  11 1
            12    5  12 1
            13   13  14 2
            14   14  15 1
            15   14  16 1
            16   14  17 2

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