KEGG   DRUG: Neramexane mesylateHelp
Entry
D05145                      Drug                                   

Name
Neramexane mesylate (USAN)
Formula
C11H23N. CH4SO3
Exact mass
265.1712
Mol weight
265.4127
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01582  N-methyl-D-aspartate receptor antagonist
 DG01498  NMDA receptor antagonist
Activity
Treatment of depression, Alzheimer's disease, and pain
Target
N-methyl-D-aspartate receptor [HSA:2902 2903 2904 2905 2906] [KO:K05208 K05209 K05210 K05211 K05212]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Long-term potentiation
Glutamatergic synapse
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Neramexane
      D05145  Neramexane mesylate (USAN)
BRITE hierarchy
Other DBs
CAS: 
457068-92-7
PubChem: 
LigandBox: 
KCF data Show

ATOM        17
            1   C1z C     8.5400  -14.4200
            2   C1x C     8.5400  -15.8200
            3   C1z C     9.7524  -16.5200
            4   C1x C    10.9649  -15.8200
            5   C1z C    10.9649  -14.4200
            6   C1x C     9.7524  -13.7200
            7   C1a C     8.7625  -17.5099
            8   C1a C    10.7424  -17.5099
            9   N1a N    12.1960  -13.7090
            10  C1a C     7.3276  -13.7200
            11  C1a C     7.3276  -15.1200
            12  C1a C    12.1961  -15.1309
            13  O1d O    17.3605  -14.8060
            14  S4a S    17.3605  -16.2024
            15  C1a C    15.9642  -16.2024
            16  O1d O    18.7569  -16.2024
            17  O1d O    17.3605  -17.5987
BOND        16
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     3   7 1
            8     3   8 1
            9     5   9 1
            10    1  10 1
            11    1  11 1
            12    5  12 1
            13   13  14 2
            14   14  15 1
            15   14  16 1
            16   14  17 2

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