KEGG   DRUG: Nesiritide citrateHelp
Entry
D05148                      Drug                                   

Name
Nesiritide citrate (USAN)
Formula
C143H244N50O42S4. (C6H8O7)x
Remark
ATC code: 
Chemical group: 
Activity
Vasodilator, Atrial natriuretic peptide receptor agonist
Comment
Recombinant of human B-type natriuretic peptide (BNP) [HSA:4879]
Renin-angiotensin system antagonist
Treatment of congestive heart failure
Target
NPR1 [HSA:4881] [KO:K12323]
  Pathway
Vascular smooth muscle contraction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01D VASODILATORS USED IN CARDIAC DISEASES
    C01DX Other vasodilators used in cardiac diseases
     C01DX19 Nesiritide
      D05148  Nesiritide citrate (USAN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Lyases
   guanylate cyclase A
    Nesiritide
     D05148  Nesiritide citrate (USAN)
BRITE hierarchy
Other DBs
CAS: 
189032-40-4
PubChem: 

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