KEGG   DRUG: D05150Help
Entry
D05150                      Drug                                   

Name
Netoglitazone (USAN/INN)
Formula
C21H16FNO3S
Exact mass
381.0835
Mol weight
381.42
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidiabetic;
Orally-administered insulin action enhancer to lower the plasma glucose in patients with non-insulin dependent diabetes mellitus [Type II]
Target
peroxisome proliferator-activated receptor (PPAR) gamma modulator [HSA:5468] [KO:K08530]
  Pathway
hsa03320  PPAR signaling pathway  
 
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) gamma
     Netoglitazone
      D05150  Netoglitazone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
161600-01-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C8x C    24.5000  -22.2600
            2   C8y C    24.5000  -23.6600
            3   C8x C    25.7124  -24.3600
            4   C8y C    26.9249  -23.6600
            5   C8y C    26.9249  -22.2600
            6   C8x C    25.7124  -21.5600
            7   C8x C    28.1373  -24.3600
            8   C8x C    29.3497  -23.6600
            9   C8y C    29.3497  -22.2600
            10  C8x C    28.1373  -21.5600
            11  C1b C    30.5473  -21.5685
            12  C1y C    31.7356  -22.2545
            13  C5x C    31.7136  -23.6600
            14  N1x N    33.0404  -24.1147
            15  C5x C    33.8828  -22.9933
            16  S2x S    33.0767  -21.8456
            17  O5x O    35.2789  -22.9456
            18  O5x O    30.5657  -24.4666
            19  O2a O    23.2876  -24.3600
            20  C1b C    22.0921  -23.6696
            21  C8y C    20.9047  -24.3551
            22  C8y C    19.7135  -23.6671
            23  C8x C    18.5010  -24.3669
            24  C8x C    18.5008  -25.7669
            25  C8x C    19.6920  -26.4549
            26  C8x C    20.9045  -25.7551
            27  X   F    19.7135  -22.2602
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   12  16 1
            19   15  17 2
            20   13  18 2
            21    2  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   21  26 1
            30   22  27 1

» Japanese version   » Back

DBGET integrated database retrieval system