KEGG   DRUG: NetoglitazoneHelp
Entry
D05150                      Drug                                   

Name
Netoglitazone (USAN/INN)
Formula
C21H16FNO3S
Exact mass
381.0835
Mol weight
381.42
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antidiabetic agent
 DG01685  Insulin sensitizer
  DG01795  PPAR gamma agonist
   DG01683  Thiazolidinedione
Other
 DG01733  PPAR agonist
  DG01683  Thiazolidinedione
Activity
Antidiabetic, Orally-administered insulin action enhancer to lower the plasma glucose in patients with non-insulin dependent diabetes mellitus [Type II]
Target
peroxisome proliferator-activated receptor (PPAR) gamma [HSA:5468] [KO:K08530]
  Pathway
PPAR signaling pathway
Interaction
Drug interaction
Structure map
Peroxisome proliferator-activated receptor (PPAR) agonists
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Thyroid hormone like receptors
   Peroxisome proliferator-activated receptor (PPAR)
    peroxisome proliferator-activated receptor (PPAR) gamma
     Netoglitazone
      D05150  Netoglitazone (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
161600-01-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        27
            1   C8x C    24.5000  -22.2600
            2   C8y C    24.5000  -23.6600
            3   C8x C    25.7124  -24.3600
            4   C8y C    26.9249  -23.6600
            5   C8y C    26.9249  -22.2600
            6   C8x C    25.7124  -21.5600
            7   C8x C    28.1373  -24.3600
            8   C8x C    29.3497  -23.6600
            9   C8y C    29.3497  -22.2600
            10  C8x C    28.1373  -21.5600
            11  C1b C    30.5473  -21.5685
            12  C1y C    31.7356  -22.2545
            13  C5x C    31.7136  -23.6600
            14  N1x N    33.0404  -24.1147
            15  C5x C    33.8828  -22.9933
            16  S2x S    33.0767  -21.8456
            17  O5x O    35.2789  -22.9456
            18  O5x O    30.5657  -24.4666
            19  O2a O    23.2876  -24.3600
            20  C1b C    22.0921  -23.6696
            21  C8y C    20.9047  -24.3551
            22  C8y C    19.7135  -23.6671
            23  C8x C    18.5010  -24.3669
            24  C8x C    18.5008  -25.7669
            25  C8x C    19.6920  -26.4549
            26  C8x C    20.9045  -25.7551
            27  X   F    19.7135  -22.2602
BOND        30
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12    9  11 1
            13   11  12 1
            14   12  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   12  16 1
            19   15  17 2
            20   13  18 2
            21    2  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   21  26 1
            30   22  27 1

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