KEGG   DRUG: Oxmetidine hydrochlorideHelp
Entry
D05306                      Drug                                   

Name
Oxmetidine hydrochloride (USAN)
Formula
C19H21N5O3S. 2HCl
Exact mass
471.0899
Mol weight
472.3886
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Gastrointestinal agent
 DG01481  Histamine receptor H2 antagonist
Unclassified
  DG01481  Histamine receptor H2 antagonist
Remark
Chemical group: 
Activity
Anti-ulcerative, H2 receptor antagonist
Target
HRH2 [HSA:3274] [KO:K04150]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H2-receptor
     Oxmetidine
      D05306  Oxmetidine hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
63204-23-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        30
            1   X   Cl   40.2718  -19.8518
            2   N5x N    32.9700  -15.9600
            3   C8y C    32.9700  -17.3600
            4   N4x N    34.1824  -18.0600
            5   C8x C    35.3949  -17.3600
            6   C8y C    35.3949  -15.9600
            7   C8y C    34.1824  -15.2600
            8   C8y C    37.8197  -15.9600
            9   C1b C    36.6073  -15.2600
            10  C8x C    37.8197  -17.3599
            11  C8x C    39.0322  -18.0599
            12  C8y C    40.2446  -17.3600
            13  C8y C    40.2446  -15.9600
            14  O2x O    41.5761  -17.7926
            15  C1x C    42.3990  -16.6600
            16  O2x O    41.5761  -15.5274
            17  C8x C    39.0322  -15.2600
            18  N1b N    31.7576  -18.0600
            19  C1b C    30.5451  -17.3600
            20  C1b C    29.3327  -18.0600
            21  S2a S    28.1203  -17.3600
            22  C1b C    26.9078  -18.0600
            23  C8y C    25.6954  -17.3600
            24  O5x O    34.1824  -13.8602
            25  N5x N    25.6954  -15.9600
            26  C8x C    24.3639  -15.5274
            27  N4x N    23.5410  -16.6600
            28  C8y C    24.3639  -17.7926
            29  C1a C    23.9346  -19.1138
            30  X   Cl   40.2718  -19.8518
BOND        31
            1     2   3 2
            2     3   4 1
            3     4   5 1
            4     5   6 2
            5     6   7 1
            6     2   7 1
            7     8   9 1
            8     6   9 1
            9     8  10 2
            10   10  11 1
            11   12  13 1
            12   12  14 1
            13   14  15 1
            14   15  16 1
            15   13  16 1
            16   11  12 2
            17   13  17 2
            18    8  17 1
            19    3  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25    7  24 2
            26   23  25 1
            27   25  26 2
            28   26  27 1
            29   27  28 1
            30   23  28 2
            31   28  29 1
BRACKET     1    38.6400  -20.5100   38.6400  -19.1800
            1    41.1600  -19.1800   41.1600  -20.5100
            1  2
 ORIGINAL  1    1
 REPEAT    1   30

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