KEGG   DRUG: Pamatolol sulfateHelp
Entry
D05345                      Drug                                   

Name
Pamatolol sulfate (USAN)
Formula
(C16H26N2O4)2. H2SO4
Exact mass
718.3459
Mol weight
718.8558
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Activity
Antiarrhythmic, beta-Adrenergic receptor antagonist
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Pamatolol
      D05345  Pamatolol sulfate (USAN)
    beta2-adrenergic receptor
     Pamatolol
      D05345  Pamatolol sulfate (USAN)
    beta3-adrenergic receptor
     Pamatolol
      D05345  Pamatolol sulfate (USAN)
BRITE hierarchy
Other DBs
CAS: 
59954-01-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        49
            1   S4a S    35.4900  -26.3200
            2   O1d O    35.4900  -24.9200
            3   O1d O    35.4900  -27.7200
            4   O1d O    34.0200  -26.3200
            5   O1d O    36.8900  -26.3200
            6   O2a O    22.2600  -21.6300
            7   C1b C    23.5200  -20.9300
            8   C1c C    24.7100  -21.6300
            9   C1b C    25.9000  -20.9300
            10  N1b N    27.0900  -21.6300
            11  C1c C    28.2800  -20.9300
            12  O1a O    24.7100  -23.0300
            13  C1a C    29.4700  -21.6300
            14  C1a C    28.2800  -19.5300
            15  C8y C    22.2428  -23.0299
            16  C8x C    21.0349  -23.7076
            17  C8x C    21.0178  -25.1075
            18  C8y C    22.2216  -25.8223
            19  C8x C    23.4294  -25.1446
            20  C8x C    23.4465  -23.7447
            21  C1b C    22.2045  -27.2299
            22  C1b C    20.9727  -27.9214
            23  N1b N    19.7928  -27.2210
            24  C7a C    18.5813  -27.9011
            25  O7a O    17.3677  -27.1803
            26  C1a C    16.1496  -27.8636
            27  O6a O    18.5645  -29.3299
            28  O2a O    22.2600  -21.6300
            29  C1b C    23.5200  -20.9300
            30  C1c C    24.7100  -21.6300
            31  C1b C    25.9000  -20.9300
            32  N1b N    27.0900  -21.6300
            33  C1c C    28.2800  -20.9300
            34  C1a C    29.4700  -21.6300
            35  C1a C    28.2800  -19.5300
            36  O1a O    24.7100  -23.0300
            37  C8y C    22.2428  -23.0299
            38  C8x C    21.0349  -23.7076
            39  C8x C    21.0178  -25.1075
            40  C8y C    22.2216  -25.8223
            41  C8x C    23.4294  -25.1446
            42  C8x C    23.4465  -23.7447
            43  C1b C    22.2045  -27.2299
            44  C1b C    20.9727  -27.9214
            45  N1b N    19.7928  -27.2210
            46  C7a C    18.5813  -27.9011
            47  O7a O    17.3677  -27.1803
            48  C1a C    16.1496  -27.8636
            49  O6a O    18.5645  -29.3299
BOND        48
            1     1   2 2
            2     1   3 2
            3     1   4 1
            4     1   5 1
            5     6   7 1
            6     7   8 1
            7     8   9 1
            8     9  10 1
            9    10  11 1
            10    8  12 1
            11   11  13 1
            12   11  14 1
            13    6  15 1
            14   15  16 2
            15   16  17 1
            16   17  18 2
            17   18  19 1
            18   19  20 2
            19   15  20 1
            20   18  21 1
            21   21  22 1
            22   22  23 1
            23   23  24 1
            24   24  25 1
            25   25  26 1
            26   24  27 2
            27   28  29 1
            28   29  30 1
            29   30  31 1
            30   31  32 1
            31   32  33 1
            32   30  36 1
            33   33  34 1
            34   33  35 1
            35   28  37 1
            36   37  38 2
            37   38  39 1
            38   39  40 2
            39   40  41 1
            40   41  42 2
            41   37  42 1
            42   40  43 1
            43   43  44 1
            44   44  45 1
            45   45  46 1
            46   46  47 1
            47   47  48 1
            48   46  49 2
BRACKET     1    14.2800  -30.1000   14.2800  -17.9900
            1    31.2900  -17.9900   31.2900  -30.1000
            1  2
 ORIGINAL  1    6   7   8   9  10  11  13  14  12  15  16  17  18  19  20  21
            1   22  23  24  25  26  27
 REPEAT    1   28  29  30  31  32  33  34  35  36  37  38  39  40  41  42  43
            1   44  45  46  47  48  49

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