KEGG   DRUG: D05366Help
Entry
D05366                      Drug                                   

Name
Procaterol hydrochloride hydrate (JP16);
Meptin (TN)
Formula
(C16H22N2O3)2. 2HCl. H2O
Exact mass
670.29
Mol weight
671.6521
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Bronchodilator [DS:H00079]
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03A ADRENERGICS, INHALANTS
    R03AC Selective beta-2-adrenoreceptor agonists
     R03AC16 Procaterol
      D05366  Procaterol hydrochloride hydrate (JP16)
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CC Selective beta-2-adrenoreceptor agonists
     R03CC08 Procaterol
      D05366  Procaterol hydrochloride hydrate (JP16)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  22  Respiratory organ agents
   225  Bronchodilators
    2259  Others
     D05366  Procaterol hydrochloride hydrate (JP16)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Procaterol
      D05366  Procaterol hydrochloride hydrate (JP16)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D05366  Procaterol hydrochloride hydrate
BRITE hierarchy
Other DBs
CAS: 
81262-93-3
PubChem: 
LigandBox: 
KCF data Show

ATOM        45
            1   X   Cl   41.1454  -16.1616
            2   C8y C    27.0814  -15.8115
            3   C8y C    27.0814  -17.2109
            4   C8y C    28.2709  -17.9106
            5   C8y C    29.5304  -17.2109
            6   C8x C    29.5304  -15.8115
            7   C8x C    28.2709  -15.1118
            8   N4x N    25.8919  -17.9106
            9   C8y C    25.8919  -19.3100
            10  C8x C    27.0814  -20.0097
            11  C8x C    28.2709  -19.3100
            12  C1c C    30.7199  -17.9106
            13  C1c C    31.9793  -17.2109
            14  N1b N    33.1688  -17.9106
            15  C1c C    34.3583  -17.2109
            16  C1a C    35.6178  -17.9106
            17  O1a O    30.7199  -19.3100
            18  C1b C    31.9793  -15.8115
            19  C1a C    34.3583  -15.8115
            20  C1a C    30.7199  -15.1118
            21  O1a O    25.8919  -15.1118
            22  O5x O    24.7024  -20.0097
            23  O0  O    41.4952  -18.6100
            24  X   Cl   41.1454  -16.1616
            25  C8y C    27.0814  -15.8115
            26  C8y C    27.0814  -17.2109
            27  C8y C    28.2709  -17.9106
            28  C8y C    29.5304  -17.2109
            29  C8x C    29.5304  -15.8115
            30  C8x C    28.2709  -15.1118
            31  C1c C    30.7199  -17.9106
            32  C1c C    31.9793  -17.2109
            33  N1b N    33.1688  -17.9106
            34  C1c C    34.3583  -17.2109
            35  C1a C    35.6178  -17.9106
            36  C1a C    34.3583  -15.8115
            37  C1b C    31.9793  -15.8115
            38  C1a C    30.7199  -15.1118
            39  O1a O    30.7199  -19.3100
            40  C8x C    28.2709  -19.3100
            41  C8x C    27.0814  -20.0097
            42  C8y C    25.8919  -19.3100
            43  N4x N    25.8919  -17.9106
            44  O5x O    24.7024  -20.0097
            45  O1a O    25.8919  -15.1118
BOND        44
            1     2   3 2
            2     3   4 1
            3     4   5 2
            4     5   6 1
            5     6   7 2
            6     2   7 1
            7     3   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 2
            11    4  11 1
            12    5  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 1
            17   12  17 1 #Up
            18   13  18 1 #Up
            19   15  19 1
            20   18  20 1
            21    2  21 1
            22    9  22 2
            23   25  26 2
            24   26  27 1
            25   27  28 2
            26   28  29 1
            27   29  30 2
            28   25  30 1
            29   26  43 1
            30   43  42 1
            31   42  41 1
            32   41  40 2
            33   27  40 1
            34   28  31 1
            35   31  32 1
            36   32  33 1
            37   33  34 1
            38   34  35 1
            39   31  39 1 #Up
            40   32  37 1 #Up
            41   34  36 1
            42   37  38 1
            43   25  45 1
            44   42  44 2
BRACKET     1    39.4100  -17.0100   39.4100  -15.3300
            1    42.0700  -15.3300   42.0700  -17.0100
            1  2
 ORIGINAL  1    1
 REPEAT    1   24
            2    22.8200  -20.8600   22.8200  -13.5100
            2    37.8700  -13.5100   37.8700  -20.8600
            2  2
 ORIGINAL  2    2   3   4   5   6   7  12  13  14  15  16  19  18  20  17  11
            2   10   9   8  22  21
 REPEAT    2   25  26  27  28  29  30  31  32  33  34  35  36  37  38  39  40
            2   41  42  43  44  45

» Japanese version   » Back

DBGET integrated database retrieval system