KEGG   DRUG: D05389Help
Entry
D05389                      Drug                                   

Name
Pegnartograstim (USAN/INN)
Sequence
MAPTYRASSL PQSFLLKSLE QVRKIQGDGA ALQEKLCATY KLCHPEELVL LGHSLGIPWA
PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL QALEGISPEL GPTLDTLQLD VADFATTIWQ
QMEELGMAPA LQPTQGAMPA FASAFQRRAG GVLVASHLQS FLEVSYRVLR HLAQP
(disulfide bridges: 37-43, 65-75)
  Type
Peptide
Activity
Parenteral adjuvant to anticancer chemotherapy;
Immunomodulator
Comment
see Nartograstim [DR:D03245]
Target
granulocyte colony stimulating factor (G-CSF) receptor agonist [HSA:1441] [KO:K05061]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   granulocyte colony stimulating factor (G-CSF) receptor [HSA:1441] [KO:K05061]
    Nartograstim
     D05389  Pegnartograstim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
204565-76-4
PubChem: 

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