| Entry |
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| Name |
Pilocarpine nitrate (USP);
Pilagan (TN)
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| Formula |
C11H16N2O2. HNO3
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| Exact mass |
271.1168
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| Mol weight |
271.2698
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| Structure |
     |
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| Activity |
Cholinergic [ophthalmic] [DS: H00612]
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| Remark |
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| Target |
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| Pathway |
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| Metabolism |
Enzyme: CYP2A6 [HSA: 1548]
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| Interaction |
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| Structure map |
| Cholinergic and anticholinergic drugs |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N07 OTHER NERVOUS SYSTEM DRUGS
N07A PARASYMPATHOMIMETICS
N07AX Other parasympathomimetics
N07AX01 Pilocarpine
D05478 Pilocarpine nitrate (USP)
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EB Parasympathomimetics
S01EB01 Pilocarpine
D05478 Pilocarpine nitrate (USP)
USP drug classification [BR:br08302]
Dental and Oral Agents
Pilocarpine
D05478 Pilocarpine nitrate (USP)
Ophthalmic Agents
Ophthalmic Antiglaucoma Agents
Cholinergic Agonists, Ophthalmic
Pilocarpine
D05478 Pilocarpine nitrate (USP)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
Pilocarpine [ATC:N07AX01 S01EB01]
D05478 Pilocarpine nitrate (USP)
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| Other DBs |
CAS: 148-72-1 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 19
1 C1y C 28.6049 -17.6741
2 C1y C 27.1960 -17.6741
3 C1b C 29.8268 -18.3174
4 C1x C 29.0492 -16.3294
5 C7x C 26.7576 -16.3294
6 C1b C 26.3656 -18.8143
7 C8y C 30.8967 -17.6799
8 O7x O 27.9034 -15.4992
9 O6a O 25.4128 -15.8909
10 C1a C 24.9625 -18.8082
11 N4y N 32.3115 -17.6799
12 C8x C 30.4524 -16.3353
13 C8x C 32.7443 -16.3353
14 C1a C 33.1359 -18.8200
15 N5x N 31.6043 -15.5050
16 N2b N 37.8531 -17.0458 #+
17 O3a O 37.8472 -15.6499
18 O3a O 39.0961 -17.7559 #-
19 O1b O 36.6419 -17.7522
BOND 19
1 1 2 1
2 1 3 1 #Down
3 1 4 1
4 2 5 1
5 2 6 1 #Down
6 3 7 1
7 4 8 1
8 5 9 2
9 6 10 1
10 7 11 1
11 7 12 2
12 11 13 1
13 11 14 1
14 12 15 1
15 5 8 1
16 13 15 2
17 16 17 2
18 16 18 1
19 16 19 1
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