KEGG   DRUG: D05587Help
Entry
D05587                      Drug                                   

Name
Practolol (USAN)
Formula
C14H22N2O3
Exact mass
266.163
Mol weight
266.3361
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-adrenergic [beta-receptor]
Remark
Same as: 
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
Antiarrhythmic drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB01 Practolol
      D05587  Practolol (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Practolol
      D05587  Practolol (USAN)
BRITE hierarchy
Other DBs
CAS: 
6673-35-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8y C    21.1225  -17.5782
            2   C8x C    22.3277  -16.8586
            3   C8x C    19.8997  -16.8935
            4   O2a O    21.1400  -18.9764
            5   C8x C    22.3044  -15.4601
            6   C8x C    19.8822  -15.4953
            7   C1b C    19.9348  -19.6903
            8   C8y C    21.0816  -14.7757
            9   C1c C    18.7179  -19.0116
            10  N1b N    21.0582  -13.3772
            11  C1b C    17.5125  -19.7254
            12  O1a O    18.6945  -17.6073
            13  C5a C    22.2576  -12.6576
            14  N1b N    16.2897  -19.0409
            15  C1a C    23.4803  -13.3363
            16  O5a O    22.2342  -11.2534
            17  C1c C    15.0903  -19.7605
            18  C1a C    13.8674  -19.0760
            19  C1a C    15.1079  -21.1588
BOND        19
            1     1   2 1
            2     1   3 2
            3     1   4 1
            4     2   5 2
            5     3   6 1
            6     4   7 1
            7     5   8 1
            8     7   9 1
            9     8  10 1
            10    9  11 1
            11    9  12 1
            12   10  13 1
            13   11  14 1
            14   13  15 1
            15   13  16 2
            16   14  17 1
            17   17  18 1
            18   17  19 1
            19    6   8 2

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