KEGG   DRUG: D05640Help
Entry
D05640                      Drug                                   

Name
Prorenoate potassium (USAN/INN)
Formula
C23H31O4. K
Exact mass
410.1859
Mol weight
410.5881
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Aldosterone antagonist
Target
mineralocorticoid receptor antagonist [HSA:4306] [KO:K08555]
  Pathway
hsa04960  Aldosterone-regulated sodium reabsorption  
 
Structure map
Glucocorticoid and meneralocorticoid receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    mineralocorticoid receptor
     Prorenoate
      D05640  Prorenoate potassium (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
49847-97-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C1y C    26.5300  -19.5300
            2   C1y C    25.4800  -18.9000
            3   C1y C    27.7200  -18.9000
            4   C1y C    26.5300  -20.9300
            5   C1z C    24.2200  -19.5300
            6   C1x C    25.4800  -17.5700
            7   C1z C    27.7200  -17.5700
            8   C1x C    30.0300  -18.9000
            9   C1y C    25.4100  -21.5600
            10  C2y C    24.2200  -20.8600
            11  C1x C    23.1000  -18.9000
            12  C1a C    24.2200  -18.2700
            13  C1x C    26.6000  -16.8700
            14  C1z C    28.9100  -16.8700
            15  C1x C    30.0300  -17.5700
            16  C2x C    23.1000  -21.5600
            17  C1x C    21.9100  -19.5300
            18  C1b C    30.0300  -16.1700
            19  O1a O    28.9100  -15.2600
            20  C5x C    21.9100  -20.8600
            21  O5x O    20.7200  -21.5600
            22  C1a C    27.7200  -16.1700
            23  C1b C    31.2662  -16.8271
            24  C6a C    32.4828  -16.0671
            25  O6a O    33.7302  -16.7301 #-
            26  O6a O    32.5050  -14.7007
            27  C1x C    26.5300  -22.3300
            28  Z   K    35.5600  -16.8000 #+
BOND        31
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     5  10 1
            9     5  11 1
            10    5  12 1 #Up
            11    6  13 1
            12    7  14 1
            13    8  15 1
            14   10  16 2
            15   11  17 1
            16   14  18 1 #Down
            17   14  19 1 #Up
            18   16  20 1
            19   20  21 2
            20    7  13 1
            21   14  15 1
            22   17  20 1
            23    7  22 1 #Up
            24    9   4 1
            25   10   9 1
            26   18  23 1
            27   23  24 1
            28   24  25 1
            29   24  26 2
            30    4  27 1
            31    9  27 1

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