| Entry |
|
|---|
| Name |
Ranitidine bismuth citrate (USAN);
Tritec (TN)
|
|---|
| Formula |
C13H22N4O3S. Bi. C6H5O7
|
|---|
| Exact mass |
712.1252
|
|---|
| Mol weight |
712.4839
|
|---|
| Structure |
     |
|---|
| Activity |
Antagonist [to histamine H2 receptors]
|
|---|
| Remark |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Transporter: SLC22A2 [HSA: 6582]
|
|---|
| Interaction |
CYP inhibition: CYP2D6 [HSA: 1565], CYP3A [KO: K07424]
Transporter inhibition: SLC22A2 [HSA: 6582]
 |
|---|
| Structure map |
| Antiulcer drugs | | Histamine H2/H3 receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
A ALIMENTARY TRACT AND METABOLISM
A02 DRUGS FOR ACID RELATED DISORDERS
A02B DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
A02BA H2-receptor antagonists
A02BA07 Ranitidine bismuth citrate
D05699 Ranitidine bismuth citrate (USAN)
USP drug classification [BR:br08302]
Gastrointestinal Agents
Histamine2 (H2) receptor Antagonists
Ranitidine
D05699 Ranitidine bismuth citrate (USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H2-receptor [HSA:3274] [KO:K04150]
Ranitidine bismuth citrate [ATC:A02BA07]
D05699 Ranitidine bismuth citrate (USAN)
 |
|---|
| Other DBs |
CAS: 128345-62-0 PubChem: LigandBox: |
|---|
| KCF data |
ATOM 35
1 C8y C 19.0764 -19.5690
2 O2x O 20.1947 -20.4079
3 C8x C 19.4958 -18.2410
4 C1b C 17.8181 -20.2680
5 C8y C 21.3131 -19.5690
6 C8x C 20.8937 -18.2410
7 N1c N 16.6297 -19.5690
8 C1b C 22.5015 -20.2680
9 C1a C 15.4415 -20.2680
10 C1a C 16.6297 -18.1711
11 S2a S 23.6898 -19.5690
12 C1b C 24.9479 -20.2680
13 C1b C 26.1363 -19.5690
14 N1b N 27.3246 -20.2680
15 C2c C 28.5828 -19.5690
16 C2b C 29.7711 -20.2680
17 N1b N 28.5828 -18.1711
18 N2b N 30.9595 -19.5690 #+
19 C1a C 27.3246 -17.4721
20 O3a O 30.9595 -18.1711 #-
21 O3a O 32.2177 -20.2680
22 C1d C 29.4061 -24.8142
23 C1b C 28.1950 -25.5105
24 C1b C 30.6174 -25.5045
25 C6a C 30.0966 -23.5970
26 O1a O 28.6981 -23.5970
27 C6a C 26.9895 -24.8200
28 C6a C 30.6057 -26.9032
29 O6a O 29.3885 -22.3801 #-
30 O6a O 31.5010 -23.5970
31 O6a O 25.7784 -25.5222 #-
32 O6a O 27.0478 -23.4217
33 O6a O 31.8170 -27.6053 #-
34 O6a O 29.3885 -27.5994
35 Z Bi 22.4698 -25.4097 #3+
BOND 33
1 1 2 1
2 1 3 2
3 1 4 1
4 2 5 1
5 3 6 1
6 4 7 1
7 5 8 1
8 7 9 1
9 7 10 1
10 8 11 1
11 11 12 1
12 12 13 1
13 13 14 1
14 14 15 1
15 15 16 2
16 15 17 1
17 16 18 1
18 17 19 1
19 18 20 1
20 18 21 2
21 5 6 2
22 22 23 1
23 22 24 1
24 22 25 1
25 22 26 1
26 23 27 1
27 24 28 1
28 25 29 1
29 25 30 2
30 27 31 1
31 27 32 2
32 28 33 1
33 28 34 2
|
|---|
