KEGG   DRUG: D05712Help
Entry
D05712                      Drug                                   

Name
Regramostim (USAN/INN)
Formula
C637H1003N171O187S8
Exact mass
14296.1998
Mol weight
14305.3332
Sequence
APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQT ITFESFKENL KDFLLVIPFD
CWEPVQE
  Type
Peptide
Activity
Antineutropenic;
Hematopoietic stimulant
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
GM-CSF receptor agonist [HSA:1438 1439] [KO:K05066 K04738]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha
    Regramostim
     D05712  Regramostim (USAN/INN)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta
    Regramostim
     D05712  Regramostim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
127757-91-9
PubChem: 

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