KEGG   DRUG: RegramostimHelp
Entry
D05712                      Drug                                   

Name
Regramostim (USAN/INN)
Formula
C637H1003N171O187S8
Exact mass
14296.1998
Mol weight
14305.3332
Sequence
APARSPSPST QPWEHVNAIQ EARRLLNLSR DTAAEMNETV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP TPETSCATQT ITFESFKENL KDFLLVIPFD
CWEPVQE
  Type
Peptide
Class
Cardiovascular agent
 DG01753  Colony stimulating factor
  DG01782  Granulocyte macrophage colony-stimulating factors (GM-CSF)
Activity
Antineutropenic, Hematopoietic stimulant
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
CSF2RA (GMCSFR, CD116) [HSA:1438] [KO:K05066];
CSF2RB (IL3RB, CD131) [HSA:1439] [KO:K04738]
  Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha
    Regramostim
     D05712  Regramostim (USAN/INN)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta
    Regramostim
     D05712  Regramostim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
127757-91-9
PubChem: 

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