KEGG   DRUG: Ridogrel
Entry
D05727                      Drug                                   
Name
Ridogrel (USAN/INN)
Formula
C18H17F3N2O3
Exact mass
366.1191
Mol weight
366.3344
Structure
Class
Blood modifier agent
 DG01950  Antithrombotic agent
  DG01712  Antiplatelet agent
   DG01516  Thromboxane A2 synthase inhibitor
Anti-allergic agent
 DG01517  Thromboxane A2 receptor antagonist
Efficacy
Antithrombotic, Thromboxane A2 (TXA2) receptor antagonist, Thromboxane synthetase inhibitor
Target
TBXA2R [HSA:6915] [KO:K04264]
TBXAS1 (CYP5A1) [HSA:6916] [KO:K01832]
  Pathway
hsa00590  Arachidonic acid metabolism
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04611  Platelet activation
Interaction
Brite
Drug groups [BR:br08330]
 Blood modifier agent
  DG01950  Antithrombotic agent
   DG01712  Antiplatelet agent
    DG01516  Thromboxane A2 synthase inhibitor
     D05727  Ridogrel
 Anti-allergic agent
  DG01517  Thromboxane A2 receptor antagonist
   D05727  Ridogrel
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Thromboxane
    TBXA2R
     D05727  Ridogrel (USAN/INN)
 Enzymes
  Isomerases (EC5)
   Thromboxane-A synthase
    TBXAS1 (CYP5A1)
     D05727  Ridogrel (USAN/INN)
Other DBs
CAS: 110140-89-1
PubChem: 47207388
LigandBox: D05727
NIKKAJI: J388.277B
KCF data

ATOM        26
            1   N5x N    28.4358  -35.0758
            2   C8x C    28.4358  -36.4811
            3   C8x C    29.6528  -37.1837
            4   C8x C    30.8698  -36.4811
            5   C8y C    30.8698  -35.0758
            6   C8x C    29.6528  -34.3732
            7   C8x C    33.3037  -36.4811
            8   C8y C    33.3037  -35.0758
            9   C2c C    32.0868  -34.3732
            10  C8y C    34.5208  -37.1837
            11  C8x C    35.7378  -36.4811
            12  C8x C    35.7378  -35.0758
            13  C8x C    34.5208  -34.3732
            14  N2b N    32.0868  -32.9679
            15  O2a O    33.3058  -32.2641
            16  C1b C    34.5068  -32.9577
            17  C1b C    35.6981  -32.2699
            18  C1b C    36.8941  -32.9607
            19  C1b C    38.0880  -32.2714
            20  C6a C    39.2826  -32.9614
            21  O6a O    40.4771  -32.2718
            22  O6a O    39.2825  -34.3730
            23  C1d C    34.5207  -38.5700
            24  X   F    33.1207  -38.5700
            25  X   F    35.9207  -38.5700
            26  X   F    34.5207  -39.9700
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     7   8 1
            8     8   9 1
            9     5   9 1
            10    7  10 2
            11   10  11 1
            12   11  12 2
            13   12  13 1
            14    8  13 2
            15    9  14 2
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   20  22 2
            24   10  23 1
            25   23  24 1
            26   23  25 1
            27   23  26 1

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Ontology (2)   
   KEGG BRITE (2)   
Drug (3)   
   KEGG DGROUP (2)   
   LigandBox (1)   
Chemical substance (3)   
   PubChem (1)   
   HMDB (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2)   
All databases (12)   

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