KEGG   DRUG: D05738Help
Entry
D05738                      Drug                                   

Name
Ritanserin (USAN/INN);
Tiserton (TN)
Formula
C27H25F2N3OS
Exact mass
477.1686
Mol weight
477.5687
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Serotonin antagonist
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157];
5-HT2C-receptor antagonist [HSA:3358] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor
     Ritanserin
      D05738  Ritanserin (USAN/INN)
    5-HT2C-receptor
     Ritanserin
      D05738  Ritanserin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
87051-43-2
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        34
            1   C2y C    29.8461  -16.1319
            2   C2c C    28.5896  -16.8300
            3   C8y C    27.4029  -16.1319
            4   C8y C    28.5896  -18.2261
            5   C8x C    26.2162  -16.8300
            6   C8x C    27.4029  -14.7358
            7   C8x C    27.3331  -18.9241
            8   C8x C    29.7763  -18.9241
            9   C8x C    24.9597  -16.1319
            10  C8x C    26.2162  -14.0377
            11  C8x C    27.3331  -20.3203
            12  C8x C    29.7763  -20.3203
            13  C8y C    24.9597  -14.7358
            14  C8y C    28.5896  -21.0183
            15  X   F    23.7730  -14.0377
            16  X   F    28.5896  -22.4144
            17  C1x C    29.8461  -14.7358
            18  C1x C    31.0328  -14.0377
            19  N1y N    32.2195  -14.7358
            20  C1x C    32.2193  -16.2017
            21  C1x C    31.0328  -16.8300
            22  C1b C    33.4760  -14.0377
            23  C1b C    34.6627  -14.7358
            24  C8y C    35.8494  -14.0377
            25  C8y C    35.8494  -12.6416
            26  N5x N    37.0361  -11.9436
            27  C8y C    38.2228  -12.6416
            28  N4y N    38.2228  -14.0377
            29  C8y C    37.0361  -14.7358
            30  C1a C    34.5929  -11.9436
            31  O5x O    37.0361  -16.1319
            32  S2x S    39.5491  -12.1530
            33  C8x C    40.3867  -13.2699
            34  C8x C    39.5491  -14.4566
BOND        38
            1     1   2 2
            2     2   3 1
            3     2   4 1
            4     3   5 2
            5     3   6 1
            6     4   7 1
            7     4   8 2
            8     5   9 1
            9     6  10 2
            10    7  11 2
            11    8  12 1
            12    9  13 2
            13   11  14 1
            14   13  15 1
            15   14  16 1
            16   10  13 1
            17   12  14 2
            18    1  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23    1  21 1
            24   19  22 1
            25   22  23 1
            26   23  24 1
            27   24  25 2
            28   25  26 1
            29   26  27 2
            30   27  28 1
            31   28  29 1
            32   24  29 1
            33   25  30 1
            34   29  31 2
            35   27  32 1
            36   32  33 1
            37   33  34 2
            38   28  34 1

» Japanese version   » Back

DBGET integrated database retrieval system