KEGG   DRUG: RuplizumabHelp
Entry
D05777                      Drug                                   

Name
Ruplizumab (USAN/INN)
Activity
Antithrombocytopenia, Immunosuppressant, Anti-CD154 antibody, Anti-CD40 ligand antibody
Comment
humanized monoclonal antibody
Treatment of immune thrombocytopenic purpura and systemic lupus erythematosus
Target
  Pathway
Cytokine-cytokine receptor interaction
Cell adhesion molecules (CAMs)
T cell receptor signaling pathway
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   CD40L (CD154)
    Ruplizumab
     D05777  Ruplizumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
220651-94-5
PubChem: 

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