KEGG   DRUG: D05777Help
Entry
D05777                      Drug                                   

Name
Ruplizumab (USAN/INN)
Activity
Treatment of immune thrombocytopenic purpura and systemic lupus erythematosus [humanized monoclonal antibody]
Target
CD154 (CD40L) [HSA:959] [KO:K03161]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04514  Cell adhesion molecules (CAMs)
hsa04660  T cell receptor signaling pathway  
 
Brite
Target-based classification of drugs [BR:br08310]
 Cytokines
  TNF family
   CD40L (CD154)
    Ruplizumab
     D05777  Ruplizumab (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
220651-94-5
PubChem: 

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