KEGG   DRUG: Sarafloxacin hydrochlorideHelp
Entry
D05802                      Drug                                   

Name
Sarafloxacin hydrochloride (USAN);
SaraFlox WSP (TN)
Formula
C20H17F2N3O3. HCl
Exact mass
421.1005
Mol weight
421.825
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Antibacterial
 DG01550  Quinolone
  DG01549  Fluoroquinolone
Other
 DG01529  Topoisomerase inhibitor
  DG01528  Topoisomerase IV inhibitor
Remark
Chemical group: 
Activity
Antibacterial, Nucleic acid biosynthesis inhibitor
Comment
Fluoroquinolones
Target
DNA gyrase [KO:K02469 K02470];
topoisomerase IV [KO:K02621 K02622]
Interaction
Drug interaction
Brite
Antiinfectives [BR:br08307]
 Antibacterials
  Nucleic acid synthesis inhibitor
   type II topoisomerase (DNA gyrase, topoisomerase IV) inhibitor
    Fluoroquinolones
     Sarafloxacin
      D05802  Sarafloxacin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
91296-87-6
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C8y C    30.4500  -32.5500
            2   C8y C    30.4500  -33.9500
            3   C8x C    31.6400  -34.6500
            4   C8y C    32.9000  -33.9500
            5   C8y C    32.9000  -32.5500
            6   C8x C    31.6400  -31.8500
            7   N4y N    34.0900  -34.6500
            8   C8x C    35.2800  -33.9500
            9   C8y C    35.2800  -32.5500
            10  C8y C    34.0900  -31.8500
            11  O5x O    34.0900  -30.4500
            12  C6a C    36.4700  -31.8500
            13  O6a O    37.6600  -32.5500
            14  O6a O    36.4700  -30.4500
            15  X   F    29.2600  -31.8500
            16  N1y N    29.2600  -34.6500
            17  C8y C    34.0900  -36.0500
            18  C8x C    32.9000  -36.7500
            19  C8x C    32.9000  -38.1500
            20  C8y C    34.0900  -38.8500
            21  C8x C    35.2800  -38.1500
            22  C8x C    35.2800  -36.7500
            23  X   F    34.0900  -40.2500
            24  C1x C    28.0700  -33.9500
            25  C1x C    26.8100  -34.6500
            26  N1x N    26.8100  -36.0500
            27  C1x C    28.0000  -36.7500
            28  C1x C    29.2600  -36.0500
            29  X   Cl   40.8100  -34.7200
BOND        31
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11    5  10 1
            12   10  11 2
            13    9  12 1
            14   12  13 1
            15   12  14 2
            16    1  15 1
            17    2  16 1
            18    7  17 1
            19   17  18 2
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   17  22 1
            25   20  23 1
            26   16  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   27  28 1
            31   16  28 1

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