KEGG   DRUG: D05803Help
Entry
D05803                      Drug                                   

Name
Sargramostim (USAN/INN);
1438 (genetical recombination) (JAN);
Leukine (TN)
Product
Activity
Antineutropenic;
Hematopoietic stimulant
Remark
ATC code: 
Comment
Recombinant GM-CSF [HSA:1437] [KO:K05427]
Target
GM-CSF receptor agonist [HSA:1438 1439] [KO:K05066 K04738]
  Pathway
hsa04060  Cytokine-cytokine receptor interaction
hsa04630  Jak-STAT signaling pathway  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
  L03 IMMUNOSTIMULANTS
   L03A IMMUNOSTIMULANTS
    L03AA Colony stimulating factors
     L03AA09 Sargramostim
      D05803  Sargramostim (genetical recombination) (JAN); Sargramostim (USAN/INN)
USP drug classification [BR:br08302]
 Blood Products/Modifiers/Volume Expanders
  Blood Formation Modifiers
   Sargramostim
    D05803  Sargramostim (genetical recombination) (JAN); Sargramostim (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Cytokine receptors
  Class I cytokine receptors (hematopoietin family receptors)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor alpha
    Sargramostim
     D05803  Sargramostim (USAN/INN); 1438 (genetical recombination) (JAN)
   granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor beta
    Sargramostim
     D05803  1438 (genetical recombination) (JAN); Sargramostim (USAN/INN)
Antineoplastics [BR:br08308]
 Biologic response modifiers
  Myeloid- and erythroid-stimulating factors
   Sargramostim
    D05803  Sargramostim (genetical recombination) (JAN); Sargramostim (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
123774-72-1
PubChem: 
DrugBank: 

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