KEGG   DRUG: D05832Help
Entry
D05832                      Drug                                   

Name
Sibenadet hydrochloride (USAN);
Viozan (TN)
Formula
C22H28N2O5S2. HCl
Exact mass
500.1206
Mol weight
501.0591
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of symptoms of chronic obstructive pulmonary disease
Remark
Drug group: 
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142];
dopamine D2-receptor agonist [HSA:1813] [KO:K04145]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04970  Salivary secretion
hsa04540  Gap junction  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Sibenadet
      D05832  Sibenadet hydrochloride (USAN)
   Dopamine
    dopamine D2-receptor
     Sibenadet
      D05832  Sibenadet hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
154189-24-9
PubChem: 
LigandBox: 
KCF data Show

ATOM        32
            1   C8y C    21.1774  -16.8165
            2   C8y C    21.1774  -18.2157
            3   C8x C    22.3901  -18.9154
            4   C8x C    23.6028  -18.2157
            5   C8y C    23.6028  -16.8165
            6   C8y C    22.3901  -16.1168
            7   C1b C    26.0282  -16.8165
            8   C1b C    24.8156  -16.1168
            9   N1b N    27.2408  -16.1168
            10  C1b C    28.4536  -16.8165
            11  S2x S    22.0995  -14.7473
            12  C8y C    20.7071  -14.6005
            13  N4x N    20.1373  -15.8793
            14  O5x O    19.9988  -13.3731
            15  O1a O    19.9963  -18.8979
            16  C1b C    29.6473  -16.1263
            17  S4a S    30.8726  -16.8332
            18  C1b C    32.0971  -16.1260
            19  C1b C    33.3224  -16.8337
            20  C1b C    34.5476  -16.1269
            21  O2a O    35.7717  -16.8347
            22  C1b C    36.9982  -16.1281
            23  C1b C    38.2210  -16.8359
            24  C8y C    39.4187  -16.1467
            25  C8x C    40.6336  -16.8504
            26  C8x C    41.8470  -16.1521
            27  C8x C    41.8489  -14.7521
            28  C8x C    40.6340  -14.0484
            29  C8x C    39.4206  -14.7467
            30  O3c O    29.8827  -17.8232
            31  O3c O    31.8626  -17.8232
            32  X   Cl   40.3200  -19.7400
BOND        33
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 2
            7     7   8 1
            8     5   8 1
            9     7   9 1
            10    9  10 1
            11    6  11 1
            12   11  12 1
            13   12  13 1
            14    1  13 1
            15   12  14 2
            16    2  15 1
            17   10  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   26  27 2
            29   27  28 1
            30   28  29 2
            31   24  29 1
            32   17  30 2
            33   17  31 2

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