KEGG   DRUG: D05939Help
Entry
D05939                      Drug                                   
Name
Sufotidine (USAN/INN)
Formula
C20H31N5O3S
Exact mass
421.2148
Mol weight
421.5568
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antagonist [to histamine H2 receptors]
Target
H2-receptor antagonist [HSA:3274] [KO:K04150]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H2-receptor [HSA:3274] [KO:K04150]
     Sufotidine
      D05939  Sufotidine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
80343-63-1
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C1x C    23.9903  -26.1180
            2   C1x C    23.9903  -27.5276
            3   C1x C    25.2109  -28.2324
            4   N1y N    26.4317  -27.5276
            5   C1x C    26.4317  -26.1180
            6   C1x C    25.2109  -25.4132
            7   C1b C    27.6712  -28.2434
            8   C8y C    28.8847  -27.5430
            9   C8x C    30.0751  -28.2305
            10  C8y C    31.2959  -27.5259
            11  C8x C    31.2961  -26.1163
            12  C8x C    30.1056  -25.4288
            13  C8x C    28.8848  -26.1334
            14  O2a O    32.5353  -28.2417
            15  C1b C    33.7472  -27.5423
            16  C1b C    34.9383  -28.2302
            17  C1b C    36.1402  -27.5363
            18  N1b N    37.3363  -28.2272
            19  C8y C    38.5356  -27.5348
            20  N5x N    39.7982  -28.0971
            21  C8y C    40.7232  -27.0701
            22  N5x N    40.0323  -25.8730
            23  N4y N    38.6802  -26.1603
            24  C1b C    42.1327  -27.0701
            25  S4a S    42.8452  -28.3032
            26  C1a C    43.5500  -29.5239
            27  O3c O    44.0907  -27.5835
            28  O3c O    41.6500  -28.9939
            29  C1a C    37.6662  -25.2470
BOND        31
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15   10  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 2
            22   20  21 1
            23   21  22 2
            24   22  23 1
            25   19  23 1
            26   21  24 1
            27   24  25 1
            28   25  26 1
            29   25  27 2
            30   25  28 2
            31   23  29 1

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