KEGG   DRUG: D05941Help
Entry
D05941                      Drug                                   

Name
Sulamserod hydrochloride (USAN)
Formula
C19H28ClN3O5S. HCl
Exact mass
481.1205
Mol weight
482.4217
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of urge incontinence;
Atrial fibrillations [selective 5-HT4 receptor antagonist]
Target
5-HT4 receptor antagonist [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor
     Sulamserod
      D05941  Sulamserod hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
184159-40-8
PubChem: 
LigandBox: 
KCF data Show

ATOM        30
            1   C5a C    29.8771  -16.0393
            2   C1b C    28.6620  -15.3378
            3   C8y C    31.1098  -15.3274
            4   C8y C    32.3151  -16.0231
            5   C8y C    33.5281  -15.3227
            6   C8y C    33.5280  -13.9220
            7   C8y C    32.3228  -13.2262
            8   C8x C    31.1098  -13.9267
            9   O2x O    32.3152  -17.4238
            10  C1x C    33.5282  -18.1240
            11  C1x C    34.7411  -17.4236
            12  O2x O    34.7411  -16.0229
            13  N1a N    34.7384  -13.2230
            14  X   Cl   32.3227  -11.8301
            15  C1b C    27.4293  -16.0499
            16  O5a O    29.8773  -17.4299
            17  C1y C    26.2162  -15.3500
            18  C1x C    26.2154  -13.9304
            19  C1x C    25.0025  -13.2312
            20  N1y N    23.7905  -13.9319
            21  C1x C    23.7914  -15.3515
            22  C1x C    25.0042  -16.0507
            23  C1b C    22.5840  -13.2363
            24  C1b C    21.3943  -13.9242
            25  N1b N    20.2032  -13.2375
            26  S4a S    19.0146  -13.9249
            27  C1a C    17.8022  -14.6249
            28  O3c O    19.7233  -15.1519
            29  O3c O    18.3230  -12.7275
            30  X   Cl   37.5900  -16.6600
BOND        31
            1     1   2 1
            2     1   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     6   7 1
            7     7   8 2
            8     3   8 1
            9     4   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13    5  12 1
            14    6  13 1
            15    7  14 1
            16    2  15 1
            17    1  16 2
            18   15  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   17  22 1
            25   20  23 1
            26   23  24 1
            27   24  25 1
            28   25  26 1
            29   26  27 1
            30   26  28 2
            31   26  29 2

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