KEGG   DRUG: D05957Help
Entry
D05957                      Drug                                   

Name
Sulfisoxazole diolamine (USAN);
Sulfafurazole diolamine;
Gantrisin (TN)
Formula
C11H13N3O3S. C4H11NO2
Exact mass
372.1467
Mol weight
372.4399
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antibacterial
Remark
ATC code: 
Target
dihydropteroate synthase inhibitor [KO:K00796]
  Pathway
ko00790  Folate biosynthesis  
 
Interaction
Drug interaction
Structure map
Sulfonamide derivatives - sulfa drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01E SULFONAMIDES AND TRIMETHOPRIM
    J01EB Short-acting sulfonamides
     J01EB05 Sulfafurazole
      D05957  Sulfisoxazole diolamine (USAN)
 S SENSORY ORGANS
  S01 OPHTHALMOLOGICALS
   S01A ANTIINFECTIVES
    S01AB Sulfonamides
     S01AB02 Sulfafurazole
      D05957  Sulfisoxazole diolamine (USAN)
Antiinfectives [BR:br08307]
 Antibacterials
  Folic acid biosynthesis inhibitor
   dihydropteroate synthase inhibitor [KO:K00796]
    Sulfonamides
     Sulfafurazole [ATC:J01EB05 S01AB02]
      D05957  Sulfisoxazole diolamine (USAN)
BRITE hierarchy
Other DBs
CAS: 
4299-60-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C8y C    10.0627  -16.2687
            2   S4a S    11.2506  -15.5698
            3   C8x C    10.0627  -17.7361
            4   C8x C     8.8048  -15.5698
            5   N1b N    12.5084  -16.2687
            6   O3c O    10.2722  -14.5915
            7   O3c O    12.2289  -14.5915
            8   C8x C     8.8747  -18.4349
            9   C8x C     7.6169  -16.3385
            10  C8y C    13.6964  -15.5698
            11  C8y C     7.6169  -17.7361
            12  N1a N     6.4289  -18.3650
            13  O2x O    14.8375  -16.3766
            14  N5x N    15.9576  -15.5406
            15  C8y C    15.5085  -14.2172
            16  C8y C    14.1111  -14.2352
            17  C1a C    16.3052  -13.0906
            18  C1a C    13.2801  -13.1218
            19  N1b N    21.8860  -16.9385
            20  C1b C    20.6703  -17.6343
            21  C1b C    23.1018  -17.6343
            22  C1b C    19.4543  -16.9385
            23  C1b C    24.3177  -16.9385
            24  O1a O    18.2385  -17.6343
            25  O1a O    25.5276  -17.6343
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     2   6 2
            6     2   7 2
            7     3   8 2
            8     4   9 1
            9     5  10 1
            10    8  11 1
            11   11  12 1
            12    9  11 2
            13   10  13 1
            14   13  14 1
            15   14  15 2
            16   15  16 1
            17   10  16 2
            18   15  17 1
            19   16  18 1
            20   19  20 1
            21   19  21 1
            22   20  22 1
            23   21  23 1
            24   22  24 1
            25   23  25 1

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