KEGG   DRUG: TiotidineHelp
Entry
D06157                      Drug                                   

Name
Tiotidine (USAN/INN)
Formula
C10H16N8S2
Exact mass
312.0939
Mol weight
312.4176
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Gastrointestinal agent
 DG01481  Histamine receptor H2 antagonist
 DG01975  Agents for peptic ulcer
  DG01481  Histamine receptor H2 antagonist
Activity
Anti-ulcerative, H2 receptor antagonist
Target
HRH2 [HSA:3274] [KO:K04150]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gastric acid secretion
Interaction
Drug interaction
Structure map
Histamine H2/H3 receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H2-receptor
     Tiotidine
      D06157  Tiotidine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
69014-14-8
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   S2x S    18.6200  -21.2800
            2   C8x C    19.4600  -22.4000
            3   C8y C    20.7200  -21.9100
            4   N5x N    20.7200  -20.5100
            5   C8y C    19.3900  -20.0900
            6   C1b C    21.9100  -22.6100
            7   S2a S    23.1000  -21.9100
            8   C1b C    24.2900  -22.6100
            9   C1b C    25.4800  -21.9100
            10  N2b N    26.6700  -22.6100
            11  C2c C    27.8600  -21.9100
            12  N1b N    29.0500  -22.6100
            13  N1b N    27.8600  -20.5100
            14  C1a C    26.6700  -19.8100
            15  C3b C    30.2400  -21.9100
            16  N3a N    31.5000  -21.2100
            17  N1b N    18.9161  -18.7726
            18  C2c C    17.5205  -18.5213
            19  N1a N    16.5939  -19.6172
            20  N2a N    17.0531  -17.2233
BOND        20
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     1   5 1
            6     3   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   11  13 1
            14   13  14 1
            15   12  15 1
            16   15  16 3
            17    5  17 1
            18   17  18 1
            19   18  19 1
            20   18  20 2

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