KEGG   DRUG: D06157Help
Entry
D06157                      Drug                                   

Name
Tiotidine (USAN/INN)
Formula
C10H16N8S2
Exact mass
312.0939
Mol weight
312.4176
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antagonist [to histamine H2 receptors]
Target
H2-receptor antagonist [HSA:3274] [KO:K04150]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04971  Gastric acid secretion  
 
Interaction
Drug interaction
Structure map
Histamine H2/H3 receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H2-receptor
     Tiotidine
      D06157  Tiotidine (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
69014-14-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   S2x S    18.6200  -21.2800
            2   C8x C    19.4600  -22.4000
            3   C8y C    20.7200  -21.9100
            4   N5x N    20.7200  -20.5100
            5   C8y C    19.3900  -20.0900
            6   C1b C    21.9100  -22.6100
            7   S2a S    23.1000  -21.9100
            8   C1b C    24.2900  -22.6100
            9   C1b C    25.4800  -21.9100
            10  N2b N    26.6700  -22.6100
            11  C2c C    27.8600  -21.9100
            12  N1b N    29.0500  -22.6100
            13  N1b N    27.8600  -20.5100
            14  C1a C    26.6700  -19.8100
            15  C3b C    30.2400  -21.9100
            16  N3a N    31.5000  -21.2100
            17  N1b N    18.9161  -18.7726
            18  C2c C    17.5205  -18.5213
            19  N1a N    16.5939  -19.6172
            20  N2a N    17.0531  -17.2233
BOND        20
            1     1   2 1
            2     2   3 2
            3     3   4 1
            4     4   5 2
            5     1   5 1
            6     3   6 1
            7     6   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   11  13 1
            14   13  14 1
            15   12  15 1
            16   15  16 3
            17    5  17 1
            18   17  18 1
            19   18  19 1
            20   18  20 2

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