KEGG   DRUG: D06172Help
Entry
D06172                      Drug                                   

Name
Tocainide (USAN/INN)
Formula
C11H16N2O
Exact mass
192.1263
Mol weight
192.2575
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiac depressant [anti-arrhythmic]
Remark
Same as: 
ATC code: 
Drug group: 
Target
voltage-gated sodium channel (SCN1A) blocker [HSA:6323] [KO:K04833];
voltage-gated sodium channel (SCN2A) blocker [HSA:6326] [KO:K04834];
voltage-gated sodium channel (SCN3A) blocker [HSA:6328] [KO:K04836];
voltage-gated sodium channel (SCN4A) blocker [HSA:6329] [KO:K04837];
voltage-gated sodium channel (SCN5A) blocker [HSA:6331] [KO:K04838];
voltage-gated sodium channel (SCN8A) blocker [HSA:6334] [KO:K04840];
voltage-gated sodium channel (SCN9A) blocker [HSA:6335] [KO:K04841]
Interaction
Drug interaction
Structure map
Antiarrhythmic drugs
Sodium channel blocking drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BB Antiarrhythmics, class Ib
     C01BB03 Tocainide
      D06172  Tocainide (USAN/INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Voltage-gated cation channels
   Na+ channel, SCN alpha, NaV1.x
    voltage-gated sodium channel (SCN1A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN2A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN3A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN4A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN5A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN8A)
     Tocainide
      D06172  Tocainide (USAN/INN)
    voltage-gated sodium channel (SCN9A)
     Tocainide
      D06172  Tocainide (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
41708-72-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        14
            1   C8y C    26.1204  -17.9085
            2   N1b N    24.9090  -17.2156
            3   C8y C    26.1145  -19.3179
            4   C8y C    27.3317  -17.2213
            5   C5a C    23.6978  -17.9028
            6   C8x C    27.3317  -20.0226
            7   C1a C    24.8974  -20.0167
            8   C8x C    28.5372  -17.9144
            9   C1a C    27.2676  -15.8121
            10  C1c C    22.4863  -17.2039
            11  O5a O    23.7618  -19.3005
            12  C8x C    28.5431  -19.3179
            13  C1a C    21.2751  -17.8969
            14  N1a N    22.4863  -15.8005
BOND        14
            1     1   2 1
            2     1   3 1
            3     1   4 2
            4     2   5 1
            5     3   6 2
            6     3   7 1
            7     4   8 1
            8     4   9 1
            9     5  10 1
            10    5  11 2
            11    6  12 1
            12   10  13 1
            13   10  14 1
            14    8  12 2

» Japanese version   » Back

DBGET integrated database retrieval system