KEGG   DRUG: D06253Help
Entry
D06253                      Drug                                   

Name
Tropanserin hydrochloride (USAN)
Formula
C17H23NO2. HCl
Exact mass
309.1496
Mol weight
309.831
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Serotonin receptor antagonist [specific in migraine]
Remark
Drug group: 
Target
5-HT2-receptor antagonist [HSA:3356 3357 3358] [KO:K04157];
5-HT3-receptor antagonist [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Interaction
Drug interaction
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2-receptor
     Tropanserin
      D06253  Tropanserin hydrochloride (USAN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from ornithine
   Tropane alkaloids
    D06253  Tropanserin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
85181-38-0
PubChem: 
LigandBox: 
KCF data Show

ATOM        21
            1   X   Cl   17.5699  -12.3199
            2   C1x C     6.1838  -10.2008
            3   C1x C     6.5119   -9.0291
            4   C1y C     7.3555   -9.9196
            5   C1y C     7.6836   -8.7479
            6   N1y N     6.4182   -7.4356
            7   C1x C     9.2302   -9.9196
            8   C1x C     8.9490   -8.7479
            9   C1y C    10.2613  -10.4820
            10  O7a O    11.3393  -11.3725
            11  C7a C    12.5579  -11.3725
            12  C8y C    13.1672  -10.2945
            13  O6a O    13.1672  -12.4973
            14  C1a C     5.6691   -6.2514
            15  C8x C    14.5600  -10.2817
            16  C8y C    15.2488   -9.0629
            17  C8x C    14.5377   -7.8570
            18  C8y C    13.1450   -7.8697
            19  C8x C    12.4561   -9.0885
            20  C1a C    12.4246   -6.6487
            21  C1a C    16.6599   -9.0503
BOND        22
            1     2   3 1
            2     2   4 1
            3     3   5 1
            4     4   6 1
            5     4   7 1
            6     5   8 1
            7     7   9 1
            8     9  10 1
            9    10  11 1
            10   11  12 1
            11   11  13 2
            12    5   6 1
            13    8   9 1
            14    6  14 1
            15   12  15 2
            16   15  16 1
            17   16  17 2
            18   17  18 1
            19   18  19 2
            20   12  19 1
            21   18  20 1
            22   16  21 1

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