KEGG   DRUG: D06330Help
Entry
D06330                      Drug                                   

Name
Xanomeline (USAN)
Formula
C14H23N3OS
Exact mass
281.1562
Mol weight
281.4169
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Alzheimer's disease treatment [cholinergic agent]
Remark
Same as: 
Drug group: 
Target
muscarinic cholinergic receptor M1, M4 agonist [HSA:1128 1132] [KO:K04129 K04132]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04725  Cholinergic synapse  
 
Interaction
Drug interaction
Structure map
Cholinergic and anticholinergic drugs
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor M1
     Xanomeline
      D06330  Xanomeline (USAN)
    muscarinic cholinergic receptor M4
     Xanomeline
      D06330  Xanomeline (USAN)
BRITE hierarchy
Other DBs
CAS: 
131986-45-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   N1y N    13.2218  -16.0130
            2   C1x C    13.2218  -17.4120
            3   C1x C    14.4333  -18.1115
            4   C2x C    15.6449  -17.4120
            5   C2y C    15.6449  -16.0130
            6   C1x C    14.4333  -15.3136
            7   C1a C    12.0102  -15.3136
            8   C8y C    16.8751  -15.3026
            9   C8y C    18.0123  -16.1056
            10  N5x N    19.1238  -15.2729
            11  S2x S    18.6753  -13.9585
            12  N5x N    17.2867  -13.9789
            13  O2a O    17.9612  -17.4810
            14  C1b C    19.1587  -18.2331
            15  C1b C    20.3945  -17.5795
            16  C1b C    21.5891  -18.3302
            17  C1b C    22.8504  -17.6636
            18  C1b C    24.0654  -18.4265
            19  C1a C    25.2866  -17.7812
BOND        20
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 2
            5     5   6 1
            6     1   6 1
            7     1   7 1
            8     5   8 1
            9     8   9 1
            10    9  10 2
            11   10  11 1
            12   11  12 1
            13    8  12 2
            14    9  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   18  19 1

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