KEGG   DRUG: D06353Help
Entry
D06353                      Drug                                   

Name
Zacopride hydrochloride (USAN)
Formula
C15H20ClN3O2. HCl. H2O
Exact mass
363.1116
Mol weight
364.2674
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-emetic;
Stimulant [peristaltic]
Remark
Drug group: 
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160];
5-HT3-receptor antagonist [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor
     Zacopride
      D06353  Zacopride hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
99617-34-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   X   Cl   21.5600  -15.8900
            2   O0  O    22.0500  -17.9200
            3   C8y C    13.7200  -19.3200
            4   C5a C    14.9100  -20.0200
            5   N1b N    16.1000  -19.3200
            6   O5a O    14.9100  -21.4200
            7   C1y C    17.2900  -20.0200
            8   C8y C    13.7200  -17.9200
            9   C8x C    12.5300  -17.2200
            10  C8y C    11.3400  -17.9200
            11  C8y C    11.3400  -19.3200
            12  C8x C    12.5300  -20.0200
            13  O2a O    14.9100  -17.2200
            14  C1a C    14.9100  -15.8200
            15  N1a N    10.1500  -17.2200
            16  X   Cl   10.1500  -20.0200
            17  C1x C    17.9200  -21.0700
            18  N1y N    19.3900  -20.3700
            19  C1x C    19.4600  -18.9700
            20  C1x C    20.9300  -21.1400
            21  C1y C    18.6900  -19.1800
            22  C1x C    18.6900  -18.2000
            23  C1x C    20.3000  -19.8800
BOND        23
            1     3   4 1
            2     4   5 1
            3     4   6 2
            4     5   7 1
            5     3   8 2
            6     8   9 1
            7     9  10 2
            8    10  11 1
            9    11  12 2
            10    3  12 1
            11    8  13 1
            12   13  14 1
            13   10  15 1
            14   11  16 1
            15   17  18 1
            16   17   7 1
            17   18  19 1
            18   18  20 1
            19   19  22 1
            20   20  23 1
            21   21  22 1
            22   21  23 1
            23   21   7 1

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