KEGG   DRUG: D06353Help
Entry
D06353                      Drug                                   
Name
Zacopride hydrochloride (USAN)
Formula
C15H20ClN3O2. HCl. H2O
Exact mass
363.1116
Mol weight
364.2674
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Anti-emetic;
Stimulant [peristaltic]
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160];
5-HT3-receptor antagonist [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Structure map
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor [HSA:3360] [KO:K04160]
     Zacopride
      D06353  Zacopride hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
99617-34-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   X   Cl   47.5788  -20.6100
            2   O0  O    48.0673  -22.7737
            3   C1y C    40.4408  -20.6990
            4   N1b N    41.4960  -21.5432
            5   C5a C    42.6919  -21.5432
            6   C8y C    43.3954  -20.4176
            7   O5a O    43.3954  -22.7390
            8   C8x C    44.7319  -20.4176
            9   C8y C    45.4354  -19.2218
            10  C1x C    39.7374  -21.7542
            11  N1y N    38.2601  -20.8397
            12  C1x C    38.2601  -19.5735
            13  C1x C    36.7125  -21.6839
            14  C1y C    39.0339  -19.7845
            15  C1x C    39.0339  -18.7997
            16  C1x C    37.4160  -20.4880
            17  C8y C    44.7319  -17.9556
            18  C8x C    43.3954  -17.9556
            19  C8y C    42.6216  -19.1514
            20  N1a N    45.4354  -16.7597
            21  X   Cl   46.8423  -19.2218
            22  O2a O    41.2146  -19.1514
            23  C1a C    40.5112  -17.9556
BOND        23
            1     3   4 1
            2     4   5 1
            3     5   6 1
            4     5   7 2
            5     6   8 1
            6     8   9 2
            7    10  11 1
            8    10   3 1
            9    11  12 1
            10   11  13 1
            11    3  14 1
            12   12  15 1
            13   13  16 1
            14   14  15 1
            15   14  16 1
            16    9  17 1
            17   17  18 2
            18   18  19 1
            19    6  19 2
            20   17  20 1
            21    9  21 1
            22   19  22 1
            23   22  23 1

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