KEGG   DRUG: Zacopride hydrochlorideHelp
Entry
D06353                      Drug                                   

Name
Zacopride hydrochloride (USAN)
Formula
C15H20ClN3O2. HCl. H2O
Exact mass
363.1116
Mol weight
364.2674
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Gastrointestinal agent
 DG01763  Propulsive
 DG01762  Antiemetic
  DG01783  Benzamide type antiemetic
Other
 DG01489  5-HT3-receptor antagonist
Activity
Anti-emetic, Stimulant [peristaltic]
Target
5-HT4-receptor [HSA:3360] [KO:K04160];
5-HT3-receptor [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
Serotonin receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor
     Zacopride
      D06353  Zacopride hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
99617-34-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        23
            1   X   Cl   21.5600  -15.8900
            2   O0  O    22.0500  -17.9200
            3   C8y C    13.7200  -19.3200
            4   C5a C    14.9100  -20.0200
            5   N1b N    16.1000  -19.3200
            6   O5a O    14.9100  -21.4200
            7   C1y C    17.2900  -20.0200
            8   C8y C    13.7200  -17.9200
            9   C8x C    12.5300  -17.2200
            10  C8y C    11.3400  -17.9200
            11  C8y C    11.3400  -19.3200
            12  C8x C    12.5300  -20.0200
            13  O2a O    14.9100  -17.2200
            14  C1a C    14.9100  -15.8200
            15  N1a N    10.1500  -17.2200
            16  X   Cl   10.1500  -20.0200
            17  C1x C    17.9200  -21.0700
            18  N1y N    19.3900  -20.3700
            19  C1x C    19.4600  -18.9700
            20  C1x C    20.9300  -21.1400
            21  C1y C    18.6900  -19.1800
            22  C1x C    18.6900  -18.2000
            23  C1x C    20.3000  -19.8800
BOND        23
            1     3   4 1
            2     4   5 1
            3     4   6 2
            4     5   7 1
            5     3   8 2
            6     8   9 1
            7     9  10 2
            8    10  11 1
            9    11  12 2
            10    3  12 1
            11    8  13 1
            12   13  14 1
            13   10  15 1
            14   11  16 1
            15   17  18 1
            16   17   7 1
            17   18  19 1
            18   18  20 1
            19   19  22 1
            20   20  23 1
            21   21  22 1
            22   21  23 1
            23   21   7 1

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