KEGG   DRUG: PramiconazoleHelp
Entry
D06630                      Drug                                   

Name
Pramiconazole (USAN/INN)
Formula
C35H39F2N7O4
Exact mass
659.3032
Mol weight
659.7255
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Antifungal
 DG01523  Triazole antifungal
Activity
Antifungal, Ergosterol biosynthesis inhibitor
Comment
Triazole derivative
Target
sterol 14alpha-demethylase [KO:K05917]
  Pathway
Steroid biosynthesis
Interaction
Drug interaction
Structure map
Antifungal agents
Brite
Antiinfectives [BR:br08307]
 Antifungals
  Ergosterol biosynthesis inhibitor
   sterol 14alpha-demethylase inhibitor
    Triazoles
     Pramiconazole
      D06630  Pramiconazole (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
219923-85-0
PubChem: 
ChEMBL: 
LigandBox: 
KCF data Show

ATOM        48
            1   O2x O    10.4980  -16.4472
            2   C1z C     9.0981  -16.4472
            3   C1x C     8.6781  -17.7771
            4   O2x O     9.7980  -18.6170
            5   C1y C    10.9179  -17.7771
            6   C1b C     7.6982  -16.4472
            7   N4y N     6.9983  -17.6371
            8   C8y C     9.7980  -15.2573
            9   C8x C    11.1979  -15.2573
            10  C8x C    11.8978  -14.0674
            11  C8y C    11.1979  -12.8075
            12  C8x C     9.7980  -12.8075
            13  C8y C     9.0981  -14.0674
            14  X   F    11.9078  -11.6010
            15  X   F     7.6983  -14.0846
            16  C8x C     5.6049  -17.7721
            17  N5x N     5.3027  -19.1390
            18  C8x C     6.5093  -19.8488
            19  N5x N     7.5572  -18.9206
            20  C1b C    12.1302  -18.4770
            21  O2a O    13.3426  -17.7771
            22  C8y C    14.7425  -17.7771
            23  C8x C    15.4485  -19.0003
            24  C8x C    16.8483  -19.0005
            25  C8y C    17.5485  -17.7882
            26  C8x C    16.8424  -16.5651
            27  C8x C    15.4426  -16.5649
            28  N1y N    18.9673  -17.7886
            29  C1x C    19.6619  -18.9925
            30  C1x C    21.0618  -18.9928
            31  N1y N    21.7620  -17.7806
            32  C1x C    21.0673  -16.5767
            33  C1x C    19.6674  -16.5764
            34  C8y C    23.1669  -17.7809
            35  C8x C    23.8650  -18.9905
            36  C8x C    25.2648  -18.9908
            37  C8y C    25.9651  -17.7787
            38  C8x C    25.2670  -16.5690
            39  C8x C    23.8672  -16.5687
            40  N1y N    27.3666  -17.7790
            41  C5x C    28.1883  -18.9105
            42  N1y N    29.5183  -18.4786
            43  C1x C    29.5186  -17.0803
            44  C1x C    28.1888  -16.6479
            45  C1c C    30.6616  -19.3099
            46  C1a C    31.9336  -18.7440
            47  C1a C    30.5141  -20.7097
            48  O5x O    27.7612  -20.2242
BOND        54
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     1   5 1
            6     2   6 1 #Up
            7     6   7 1
            8     8   9 2
            9     9  10 1
            10   10  11 2
            11   11  12 1
            12   12  13 2
            13    8  13 1
            14    2   8 1 #Down
            15   11  14 1
            16   13  15 1
            17    7  16 1
            18   16  17 2
            19   17  18 1
            20   18  19 2
            21    7  19 1
            22    5  20 1 #Up
            23   20  21 1
            24   21  22 1
            25   22  23 2
            26   23  24 1
            27   24  25 2
            28   25  26 1
            29   26  27 2
            30   22  27 1
            31   25  28 1
            32   28  29 1
            33   29  30 1
            34   30  31 1
            35   31  32 1
            36   32  33 1
            37   28  33 1
            38   31  34 1
            39   34  35 2
            40   35  36 1
            41   36  37 2
            42   37  38 1
            43   38  39 2
            44   34  39 1
            45   37  40 1
            46   40  41 1
            47   41  42 1
            48   42  43 1
            49   43  44 1
            50   40  44 1
            51   42  45 1
            52   45  46 1
            53   45  47 1
            54   41  48 2

» Japanese version   » Back

DBGET integrated database retrieval system