KEGG   DRUG: D06632Help
Entry
D06632                      Drug                                   

Name
Pruvanserin (USAN/INN)
Formula
C22H21FN4O
Exact mass
376.1699
Mol weight
376.4267
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Insomnia, major depression, and schizophrenia
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor [HSA:3356] [KO:K04157]
     Pruvanserin
      D06632  Pruvanserin (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
443144-26-1
PubChem: 
LigandBox: 
KCF data Show

ATOM        28
            1   C8x C    11.9000  -24.4300
            2   C8x C    11.9000  -25.8300
            3   C8x C    13.1124  -26.5300
            4   C8y C    14.3249  -25.8300
            5   C8y C    14.3249  -24.4300
            6   C8y C    13.1124  -23.7300
            7   C8y C    15.6564  -26.2626
            8   C8x C    16.4793  -25.1300
            9   N4x N    15.6564  -23.9974
            10  C3b C    16.0875  -27.5894
            11  C5a C    13.1124  -22.3302
            12  O5a O    11.8832  -21.6203
            13  N1y N    14.3080  -21.6398
            14  C1x C    15.4952  -22.3252
            15  C1x C    16.7076  -21.6253
            16  N1y N    16.7077  -20.2253
            17  C1x C    15.5205  -19.5398
            18  C1x C    14.3081  -20.2398
            19  C1b C    17.9346  -19.5167
            20  C1b C    19.1418  -20.2135
            21  C8y C    20.3232  -19.5313
            22  C8x C    21.5176  -20.2210
            23  C8x C    22.7301  -19.5210
            24  C8y C    22.7301  -18.1210
            25  C8x C    21.5357  -17.4314
            26  C8x C    20.3232  -18.1313
            27  X   F    23.9534  -17.4146
            28  N3a N    16.4499  -28.9417
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    5   9 1
            11    7  10 1
            12    6  11 1
            13   11  12 2
            14   11  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   13  18 1
            21   16  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   21  26 1
            30   24  27 1
            31   10  28 3

» Japanese version   » Back

DBGET integrated database retrieval system