KEGG   DRUG: D06633Help
Entry
D06633                      Drug                                   

Name
Pruvanserin hydrochloride (USAN)
Formula
C22H21FN4O. HCl
Exact mass
412.1466
Mol weight
412.8877
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Insomnia, major depression, and schizophrenia
Remark
Drug group: 
Target
5-HT2A-receptor antagonist [HSA:3356] [KO:K04157]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04726  Serotonergic synapse  
 
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT2A-receptor
     Pruvanserin
      D06633  Pruvanserin hydrochloride (USAN)
BRITE hierarchy
Other DBs
CAS: 
443144-27-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        29
            1   C8x C    25.6523  -18.6862
            2   C8x C    25.6523  -20.0900
            3   C8x C    26.8680  -20.7919
            4   C8y C    28.0837  -20.0900
            5   C8y C    28.0837  -18.6862
            6   C8y C    26.8680  -17.9843
            7   C8y C    29.4188  -20.5238
            8   C8x C    30.2440  -19.3881
            9   N4x N    29.4188  -18.2525
            10  C3b C    29.8511  -21.8542
            11  C5a C    26.8680  -16.5807
            12  O5a O    25.6354  -15.8689
            13  N1y N    28.0668  -15.8885
            14  C1x C    29.2572  -16.5757
            15  C1x C    30.4729  -15.8739
            16  N1y N    30.4730  -14.4701
            17  C1x C    29.2826  -13.7828
            18  C1x C    28.0669  -14.4847
            19  C1b C    31.7032  -13.7596
            20  C1b C    32.9137  -14.4583
            21  C8y C    34.0983  -13.7743
            22  C8x C    35.2959  -14.4658
            23  C8x C    36.5117  -13.7639
            24  C8y C    36.5117  -12.3601
            25  C8x C    35.3141  -11.6687
            26  C8x C    34.0983  -12.3705
            27  X   F    37.7383  -11.6518
            28  N3a N    30.2145  -23.2102
            29  X   Cl   34.3000  -18.2000
BOND        31
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    5   9 1
            11    7  10 1
            12    6  11 1
            13   11  12 2
            14   11  13 1
            15   13  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   13  18 1
            21   16  19 1
            22   19  20 1
            23   20  21 1
            24   21  22 2
            25   22  23 1
            26   23  24 2
            27   24  25 1
            28   25  26 2
            29   21  26 1
            30   24  27 1
            31   10  28 3

» Japanese version   » Back

DBGET integrated database retrieval system