KEGG   DRUG: D06676Help
Entry
D06676                      Drug                                   

Name
Raltegravir (USAN/INN);
MK-0518
Formula
C20H21FN6O5
Exact mass
444.1557
Mol weight
444.4163
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antivirals [DS:H00406]
Remark
ATC code: 
Target
HIV-1 integrase inhibitor
Metabolism
Enzyme: UGT1A1 [HSA:54658]
Interaction
Drug interaction
Structure map
Anti-HIV agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J05 ANTIVIRALS FOR SYSTEMIC USE
   J05A DIRECT ACTING ANTIVIRALS
    J05AX Other antivirals
     J05AX08 Raltegravir
      D06676  Raltegravir (USAN/INN)
USP drug classification [BR:br08302]
 Antivirals
  Anti-HIV Agents, Integrase Inhibitors (INSTI)
   Raltegravir
    D06676  Raltegravir (USAN/INN)
  Anti-HIV Agents, Other
   Raltegravir
    D06676  Raltegravir (USAN/INN)
Antiinfectives [BR:br08307]
 Antivirals
  Anti-HIV agent
   Ohters
    HIV-1 integrase inhibitor
     Raltegravir [ATC:J05AX08]
      D06676  Raltegravir (USAN/INN)
BRITE hierarchy
Other DBs
CAS: 
518048-05-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        32
            1   C8y C    13.8344  -20.3696
            2   C5a C    15.0467  -19.6696
            3   N1b N    16.2591  -20.3696
            4   C1d C    17.4716  -19.6696
            5   C8y C    18.6839  -20.3696
            6   N5x N    19.8963  -19.6696
            7   C8y C    21.1088  -20.3696
            8   C5a C    22.3211  -19.6696
            9   N1b N    23.5336  -20.3696
            10  C1b C    24.7459  -19.6696
            11  C8y C    25.9583  -20.3696
            12  C8x C    27.1708  -19.6696
            13  C8x C    28.3831  -20.3696
            14  N4y N    18.6839  -21.7695
            15  C8y C    19.8963  -22.4695
            16  C8y C    21.1088  -21.7695
            17  C8x C    25.9583  -21.7695
            18  C8x C    27.1708  -22.4695
            19  C8y C    28.3831  -21.7695
            20  O5a O    22.3211  -18.2696
            21  O5x O    19.8963  -23.8694
            22  C1a C    17.4756  -22.4672
            23  O1a O    22.3438  -22.4829
            24  C1a C    16.6300  -18.5723
            25  C1a C    18.1715  -18.4572
            26  O5a O    15.0467  -18.2696
            27  O2x O    12.6959  -19.5594
            28  C8y C    11.5697  -20.3909
            29  N5x N    12.0122  -21.7190
            30  N5x N    13.4122  -21.7083
            31  C1a C    10.2106  -19.9609
            32  X   F    29.5697  -22.4550
BOND        34
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 2
            6     6   7 1
            7     7   8 1
            8     8   9 1
            9     9  10 1
            10   10  11 1
            11   11  12 2
            12   12  13 1
            13    5  14 1
            14   14  15 1
            15   15  16 1
            16   16   7 2
            17   11  17 1
            18   17  18 2
            19   18  19 1
            20   19  13 2
            21    8  20 2
            22   15  21 2
            23   14  22 1
            24   16  23 1
            25    4  24 1
            26    4  25 1
            27    2  26 2
            28    1  27 1
            29   27  28 1
            30   28  29 2
            31   29  30 1
            32    1  30 2
            33   28  31 1
            34   19  32 1

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