KEGG   DRUG: EptifibatideHelp
Entry
D06888                      Drug                                   

Name
Eptifibatide (INN);
Integrilin (TN)
Product
  Generic
Formula
C35H49N11O9S2
Exact mass
831.3156
Mol weight
831.9619
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01712  Antiplatelet agent
  DG01712  Antiplatelet agent
 DG01811  Fibrinogen receptor antagonist
Remark
ATC code: 
Activity
Platelet aggregation inhibitor, Glycoproein IIb/IIIa receptor antagonist
Comment
Indication: Acute coronary syndrome
Target
ITGA2B/ITGB3 [HSA:3674 3690] [KO:K06476 K06493]
  Pathway
Focal adhesion
ECM-receptor interaction
Interaction
Drug interaction
Structure map
Antithrombosis agents
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 B BLOOD AND BLOOD FORMING ORGANS
  B01 ANTITHROMBOTIC AGENTS
   B01A ANTITHROMBOTIC AGENTS
    B01AC Platelet aggregation inhibitors excl. heparin
     B01AC16 Eptifibatide
      D06888  Eptifibatide (INN)
Target-based classification of drugs [BR:br08310]
 Others
  Cell adhesion molecules (CAMs)
   glycoprotein alpha IIb/beta3 (GPIIb/IIIa) receptor
    Eptifibatide
     D06888  Eptifibatide (INN)
BRITE hierarchy
Other DBs
CAS: 
188627-80-7
PubChem: 
DrugBank: 
LigandBox: 
KCF data Show

ATOM        57
            1   C1b C    18.7088  -13.7108
            2   C5a C    19.8059  -12.8468
            3   N1b N    21.1717  -13.1584
            4   C1c C    21.7738  -14.4120
            5   C1b C    18.7088  -15.1203
            6   C5a C    21.1726  -15.6797
            7   N1b N    19.8059  -15.9914
            8   C1b C    17.4960  -13.0106
            9   S3a S    16.2830  -13.7108
            10  N1b N    16.2830  -15.1203
            11  C5a C    17.4960  -15.8206
            12  S3a S    15.0702  -13.0106
            13  C1b C    13.8574  -13.7108
            14  C5a C    13.8574  -15.1203
            15  C1c C    15.0702  -15.8206
            16  C1c C    12.6445  -13.0106
            17  N1b N    11.4317  -13.7108
            18  C1c C    11.4317  -15.1203
            19  N1b N    12.6445  -15.8206
            20  C5a C    10.2188  -13.0106
            21  C1y C     9.0059  -13.7108
            22  N1y N     9.0059  -15.1203
            23  C5a C    10.2188  -15.8206
            24  C1x C     7.6655  -13.2753
            25  C1x C     6.8370  -14.4156
            26  C1x C     7.6655  -15.5559
            27  O5a O    19.4918  -11.4542
            28  O5a O    22.0432  -16.7652
            29  O5a O    17.4959  -17.2273
            30  O5a O    13.8573  -16.5271
            31  O5a O    10.2187  -17.2274
            32  O5a O    10.2188  -11.6254
            33  C5a C    12.6449  -11.6258
            34  C1b C    11.4318  -16.5270
            35  O5a O    13.8817  -10.9118
            36  N1a N    11.4561  -10.9388
            37  C1b C    15.0703  -17.2273
            38  C6a C    16.1138  -18.1470
            39  O6a O    17.5084  -18.1449
            40  O6a O    15.6221  -19.4512
            41  C8y C    12.5155  -17.3949
            42  C8y C    12.0831  -18.6924
            43  C8y C    13.1918  -19.5005
            44  N4x N    14.3028  -18.6958
            45  C8x C    13.8809  -17.3903
            46  C8x C    10.7241  -19.4142
            47  C8x C    10.7347  -20.8147
            48  C8x C    11.9280  -21.4916
            49  C8x C    13.1355  -20.7822
            50  C1b C    23.0144  -13.7651
            51  C1b C    24.2287  -14.5371
            52  C1b C    25.4597  -13.8950
            53  C1b C    26.6501  -14.6525
            54  N1b N    27.9233  -13.9887
            55  C2c C    29.1261  -14.7540
            56  N1a N    30.3635  -14.1090
            57  N2a N    29.1348  -16.1754
BOND        60
            1     3   4 1
            2     4   6 1
            3     2   3 1
            4     5   7 1
            5     1   2 1
            6     6   7 1
            7     1   8 1
            8     8   9 1
            9    10  11 1
            10    5  11 1
            11    9  12 1
            12   12  13 1
            13   14  15 1
            14   10  15 1
            15   13  16 1
            16   16  17 1
            17   18  19 1
            18   14  19 1
            19   17  20 1
            20   20  21 1
            21   21  22 1
            22   22  23 1
            23   18  23 1
            24   21  24 1
            25   24  25 1
            26   25  26 1
            27   22  26 1
            28    2  27 2
            29    6  28 2
            30   11  29 2
            31   14  30 2
            32   23  31 2
            33   20  32 2
            34   16  33 1
            35   18  34 1
            36   33  35 2
            37   33  36 1
            38   15  37 1
            39   37  38 1
            40   38  39 2
            41   38  40 1
            42   34  41 1
            43   41  42 1
            44   42  43 1
            45   43  44 1
            46   44  45 1
            47   41  45 2
            48   42  46 2
            49   46  47 1
            50   47  48 2
            51   48  49 1
            52   43  49 2
            53    4  50 1
            54   50  51 1
            55   51  52 1
            56   52  53 1
            57   53  54 1
            58   54  55 1
            59   55  56 1
            60   55  57 2

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