KEGG   DRUG: AcamprosateHelp
Entry
D07058                      Drug                                   

Name
Acamprosate (INN);
Aotal (TN)
Formula
C5H11NO4S
Exact mass
181.0409
Mol weight
181.2101
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Neuropsychiatric agent
 DG01498  NMDA receptor antagonist
Other
 DG01718  Drugs for addictive disorder
  DG01716  Drugs for alcohol dependence
Remark
ATC code: 
Chemical group: 
Activity
Antialcohol dependence, NMDA receptor antagonist
Comment
Alcohol withdrawal agent
Target
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Glutamatergic synapse
Alcoholism
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N07 OTHER NERVOUS SYSTEM DRUGS
   N07B DRUGS USED IN ADDICTIVE DISORDERS
    N07BB Drugs used in alcohol dependence
     N07BB03 Acamprosate
      D07058  Acamprosate (INN)
USP drug classification [BR:br08302]
 Anti-Addiction/Substance Abuse Treatment Agents
  Alcohol Deterrents/Anti-craving
   Acamprosate
    D07058  Acamprosate (INN)
Target-based classification of drugs [BR:br08310]
 Ion channels
  Glutamate-gated cation channels
   Glutamate (ionotropic), NMDA
    N-methyl-D-aspartate receptor
     Acamprosate
      D07058  Acamprosate (INN)
BRITE hierarchy
Other DBs
CAS: 
77337-76-9
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        11
            1   C1a C    26.3833  -17.1326
            2   C5a C    27.5817  -17.8244
            3   N1b N    28.7800  -17.1326
            4   C1b C    29.9783  -17.8244
            5   C1b C    31.1766  -17.1326
            6   C1b C    32.3750  -17.8244
            7   S4a S    33.5734  -17.1326
            8   O5a O    27.5817  -19.2082
            9   O1d O    34.7858  -17.8327
            10  O1d O    34.7858  -16.4326
            11  O1d O    32.3609  -16.4326
BOND        10
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     6   7 1
            7     2   8 2
            8     7   9 1
            9     7  10 2
            10    7  11 2

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