KEGG   DRUG: D07125Help
Entry
D07125                      Drug                                   

Name
Alimemazine (INN);
Trimeprazine (BAN);
Repeltin (TN)
Formula
C18H22N2S
Exact mass
298.1504
Mol weight
298.4457
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihistaminic, H1-receptor antagonist, Neuroleptic
Remark
Same as: 
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Phenothiazines
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AD Phenothiazine derivatives
     R06AD01 Alimemazine
      D07125  Alimemazine (INN); Trimeprazine (BAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Second-class OTC drugs
  Inorganic and organic chemicals
   Alimemazine
    D07125  Alimemazine (INN); Trimeprazine (BAN)
 Third-class OTC drugs
  Inorganic and organic chemicals
   Alimemazine
    D07125  Alimemazine (INN); Trimeprazine (BAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor
     Alimemazine
      D07125  Alimemazine (INN); Trimeprazine (BAN)
BRITE hierarchy
Other DBs
CAS: 
84-96-8
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8y C    25.6200  -20.5800
            2   N1y N    26.8800  -19.8800
            3   C8y C    25.6200  -21.9100
            4   C8x C    24.4300  -19.8800
            5   C8y C    28.0700  -20.5800
            6   C1b C    26.8800  -18.4100
            7   S2x S    26.8800  -22.6800
            8   C8x C    24.4300  -22.6100
            9   C8x C    23.2400  -20.5800
            10  C8y C    28.0700  -21.9800
            11  C8x C    29.2600  -19.8800
            12  C1c C    28.0700  -17.7100
            13  C8x C    23.2400  -21.9100
            14  C8x C    29.2600  -22.6800
            15  C8x C    30.5200  -20.5800
            16  C1b C    28.0700  -16.3100
            17  C1a C    29.2600  -18.4800
            18  C8x C    30.5200  -21.9100
            19  N1c N    29.2600  -15.6100
            20  C1a C    30.5200  -16.3800
            21  C1a C    29.2600  -14.2100
BOND        23
            1    12  16 1
            2    12  17 1
            3    14  18 2
            4    16  19 1
            5    19  20 1
            6    19  21 1
            7     7  10 1
            8     9  13 1
            9    15  18 1
            10    1   2 1
            11    1   3 2
            12    1   4 1
            13    2   5 1
            14    2   6 1
            15    3   7 1
            16    3   8 1
            17    4   9 2
            18    5  10 2
            19    5  11 1
            20    6  12 1
            21    8  13 2
            22   10  14 1
            23   11  15 2

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