KEGG   DRUG: D07181Help
Entry
D07181                      Drug                                   

Name
Mepindolol (INN)
Formula
C15H22N2O2
Exact mass
262.1681
Mol weight
262.3474
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Cardiovascular
Remark
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA14 Mepindolol
      D07181  Mepindolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
    beta2-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
    beta3-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
BRITE hierarchy
Other DBs
CAS: 
23694-81-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8y C    17.3600   -9.9400
            2   C8y C    17.3600  -11.3400
            3   C8y C    18.6200   -9.2400
            4   C8x C    16.0300   -9.5200
            5   N4x N    16.0300  -11.8300
            6   C8x C    18.6200  -12.0400
            7   C8x C    19.8100   -9.9400
            8   O2a O    18.6200   -7.8400
            9   C8y C    15.2600  -10.6400
            10  C8x C    19.8100  -11.3400
            11  C1b C    19.8100   -7.1400
            12  C1c C    21.0000   -7.8400
            13  C1b C    22.2600   -7.1400
            14  O1a O    21.0000   -9.2400
            15  N1b N    23.3800   -7.8400
            16  C1c C    24.5700   -7.1400
            17  C1a C    25.8300   -7.8400
            18  C1a C    24.5700   -5.7400
            19  C1a C    13.8601  -10.6204
BOND        20
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 2
            9     6  10 2
            10    8  11 1
            11   11  12 1
            12   12  13 1
            13   12  14 1
            14   13  15 1
            15   15  16 1
            16   16  17 1
            17   16  18 1
            18    5   9 1
            19    7  10 1
            20    9  19 1

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