KEGG   DRUG: MepindololHelp
Entry
D07181                      Drug                                   

Name
Mepindolol (INN)
Formula
C15H22N2O2
Exact mass
262.1681
Mol weight
262.3474
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Cardiovascular agent
 DG01466  Adrenergic receptor antagonist
  DG01464  beta-Adrenergic receptor antagonist
   DG01461  beta1-Adrenergic receptor antagonist
   DG01462  beta2-Adrenergic receptor antagonist
   DG01463  beta3-Adrenergic receptor antagonist
Remark
ATC code: 
Activity
Antiglaucoma, beta-Adrenergic receptor antagonist
Comment
Propranolol derivative
Target
ADRB1 [HSA:153] [KO:K04141];
ADRB2 [HSA:154] [KO:K04142];
ADRB3 [HSA:155] [KO:K04143]
  Pathway
Calcium signaling pathway
Neuroactive ligand-receptor interaction
Adrenergic signaling in cardiomyocytes
Salivary secretion
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA14 Mepindolol
      D07181  Mepindolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
    beta2-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
    beta3-adrenergic receptor
     Mepindolol
      D07181  Mepindolol (INN)
BRITE hierarchy
Other DBs
CAS: 
23694-81-7
PubChem: 
ChEMBL: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        19
            1   C8y C    17.3600   -9.9400
            2   C8y C    17.3600  -11.3400
            3   C8y C    18.6200   -9.2400
            4   C8x C    16.0300   -9.5200
            5   N4x N    16.0300  -11.8300
            6   C8x C    18.6200  -12.0400
            7   C8x C    19.8100   -9.9400
            8   O2a O    18.6200   -7.8400
            9   C8y C    15.2600  -10.6400
            10  C8x C    19.8100  -11.3400
            11  C1b C    19.8100   -7.1400
            12  C1c C    21.0000   -7.8400
            13  C1b C    22.2600   -7.1400
            14  O1a O    21.0000   -9.2400
            15  N1b N    23.3800   -7.8400
            16  C1c C    24.5700   -7.1400
            17  C1a C    25.8300   -7.8400
            18  C1a C    24.5700   -5.7400
            19  C1a C    13.8601  -10.6204
BOND        20
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 2
            9     6  10 2
            10    8  11 1
            11   11  12 1
            12   12  13 1
            13   12  14 1
            14   13  15 1
            15   15  16 1
            16   16  17 1
            17   16  18 1
            18    5   9 1
            19    7  10 1
            20    9  19 1

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