KEGG   DRUG: D07183Help
Entry
D07183                      Drug                                   

Name
Cloranolol (INN)
Formula
C13H19Cl2NO2
Exact mass
291.0793
Mol weight
292.2015
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA27 Cloranolol
      D07183  Cloranolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
    beta2-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
    beta3-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
BRITE hierarchy
Other DBs
CAS: 
39563-28-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   C8x C    18.7107  -17.2347
            2   C8x C    18.7107  -18.6297
            3   C8y C    19.9188  -19.3272
            4   C8x C    21.1270  -18.6297
            5   C8y C    21.1270  -17.2347
            6   C8y C    19.9188  -16.5372
            7   O2a O    22.3600  -16.5372
            8   C1b C    23.5682  -17.2347
            9   C1c C    24.7763  -16.5372
            10  C1b C    25.9843  -17.2347
            11  N1b N    27.1925  -16.5372
            12  C1d C    28.4006  -17.2347
            13  C1a C    29.5963  -17.9421
            14  X   Cl   19.9188  -15.1424
            15  X   Cl   19.9188  -20.7220
            16  O1a O    24.7763  -15.1422
            17  C1a C    29.1006  -16.0223
            18  C1a C    27.7006  -18.4472
BOND        18
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14    6  14 1
            15    3  15 1
            16    9  16 1
            17   12  17 1
            18   12  18 1

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