KEGG   DRUG: D07183Help
Entry
D07183                      Drug                                   

Name
Cloranolol (INN)
Formula
C13H19Cl2NO2
Exact mass
291.0793
Mol weight
292.2015
Structure
Mol fileKCF fileDB searchJmolKegDraw
Remark
ATC code: 
Drug group: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AA Beta blocking agents, non-selective
     C07AA27 Cloranolol
      D07183  Cloranolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
    beta2-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
    beta3-adrenergic receptor
     Cloranolol
      D07183  Cloranolol (INN)
BRITE hierarchy
Other DBs
CAS: 
39563-28-5
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        18
            1   O2a O    16.8000  -17.5700
            2   C1b C    18.0600  -16.8700
            3   C1c C    19.2500  -17.5700
            4   C1b C    20.4400  -16.8700
            5   N1b N    21.6300  -17.5700
            6   C1d C    22.8900  -16.8700
            7   O1a O    19.2500  -18.9700
            8   C1a C    24.0907  -17.5899
            9   C1a C    22.9131  -15.4702
            10  C1a C    24.1024  -16.1700
            11  C8y C    16.7828  -18.9699
            12  C8y C    15.5749  -19.6476
            13  C8x C    15.5578  -21.0475
            14  C8x C    16.7616  -21.7623
            15  C8y C    17.9694  -21.0846
            16  C8x C    17.9865  -19.6847
            17  X   Cl   14.3558  -18.9232
            18  X   Cl   19.1817  -21.8047
BOND        18
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     4   5 1
            5     5   6 1
            6     3   7 1
            7     6   8 1
            8     6   9 1
            9     6  10 1
            10    1  11 1
            11   11  12 2
            12   12  13 1
            13   13  14 2
            14   14  15 1
            15   15  16 2
            16   11  16 1
            17   12  17 1
            18   15  18 1

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