KEGG   DRUG: D07184Help
Entry
D07184                      Drug                                   

Name
Talinolol (INN)
Formula
C20H33N3O3
Exact mass
363.2522
Mol weight
363.4943
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
beta-Adrenergic blocking agent
Remark
ATC code: 
Target
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Metabolism
Transporter: ABCB1 [HSA:5243]
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C07 BETA BLOCKING AGENTS
   C07A BETA BLOCKING AGENTS
    C07AB Beta blocking agents, selective
     C07AB13 Talinolol
      D07184  Talinolol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta1-adrenergic receptor
     Talinolol
      D07184  Talinolol (INN)
BRITE hierarchy
Other DBs
CAS: 
57460-41-0
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8x C    22.3501  -17.9478
            2   C8y C    22.3501  -19.3442
            3   C8x C    23.5595  -20.0424
            4   C8x C    24.7689  -19.3442
            5   C8y C    24.7689  -17.9478
            6   C8x C    23.5595  -17.2495
            7   N1b N    21.1408  -20.0424
            8   C5a C    19.9314  -19.3442
            9   N1b N    18.7220  -20.0424
            10  C1y C    17.5127  -19.3442
            11  C1x C    17.5127  -17.9479
            12  C1x C    16.3033  -17.2496
            13  C1x C    15.0940  -17.9479
            14  C1x C    15.0940  -19.3442
            15  C1x C    16.3033  -20.0424
            16  O5a O    19.9314  -17.9480
            17  O2a O    26.0032  -17.2495
            18  C1b C    27.2127  -17.9478
            19  C1c C    28.4220  -17.2495
            20  C1b C    29.6313  -17.9478
            21  N1b N    30.8407  -17.2495
            22  C1d C    32.0501  -17.9478
            23  C1a C    33.2594  -18.6460
            24  O1a O    28.4220  -15.8531
            25  C1a C    32.7786  -16.7185
            26  C1a C    31.3510  -19.1272
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     2   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   10  15 1
            17    8  16 2
            18    5  17 1
            19   17  18 1
            20   18  19 1
            21   19  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 1
            25   19  24 1
            26   22  25 1
            27   22  26 1

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