KEGG   DRUG: D07198Help
Entry
D07198                      Drug                                   

Name
Chlorphenoxamine (INN)
Formula
C18H22ClNO
Exact mass
303.139
Mol weight
303.8264
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiallergic;
Histamine, H1-receptor antagonist
Remark
ATC code: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Structure map
Histamine H1 receptor antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D04 ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
   D04A ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
    D04AA Antihistamines for topical use
     D04AA34 Chlorphenoxamine
      D07198  Chlorphenoxamine (INN)
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AA Aminoalkyl ethers
     R06AA06 Chlorphenoxamine
      D07198  Chlorphenoxamine (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Histamine
    H1-receptor [HSA:3269] [KO:K04149]
     Chlorphenoxamine [ATC:D04AA34 R06AA06]
      D07198  Chlorphenoxamine (INN)
BRITE hierarchy
Other DBs
CAS: 
77-38-3
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8x C    15.2600  -23.6600
            2   C8y C    15.2600  -25.0600
            3   C8x C    16.4724  -25.7600
            4   C8x C    17.6849  -25.0600
            5   C8y C    17.6849  -23.6600
            6   C8x C    16.4724  -22.9600
            7   C1d C    18.9160  -22.9490
            8   C8y C    20.1212  -23.6447
            9   C8x C    20.1216  -25.0596
            10  C8x C    21.3342  -25.7593
            11  C8x C    22.5465  -25.0589
            12  C8x C    22.5460  -23.6439
            13  C8x C    21.3334  -22.9443
            14  O2a O    18.9157  -21.5601
            15  C1b C    20.1162  -20.8666
            16  C1b C    21.3062  -21.5535
            17  N1c N    22.4960  -20.8662
            18  C1a C    23.6863  -21.5532
            19  C1a C    22.4959  -19.4602
            20  C1a C    17.7036  -22.2490
            21  X   Cl   14.0476  -25.7600
BOND        22
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 2
            10    9  10 1
            11   10  11 2
            12   11  12 1
            13   12  13 2
            14    8  13 1
            15    7  14 1
            16   14  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   17  19 1
            21    7  20 1
            22    2  21 1

» Japanese version   » Back

DBGET integrated database retrieval system