KEGG   DRUG: D07337Help
Entry
D07337                      Drug                                   

Name
Nialamide (INN);
Niamid (TN)
Formula
C16H18N4O2
Exact mass
298.143
Mol weight
298.3397
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antidepressant, MAO-inhibitor
Remark
ATC code: 
Target
monoamine oxidase inhibitor [HSA:4128 4129] [KO:K00274]
  Pathway
hsa00260  Glycine, serine and threonine metabolism
hsa00330  Arginine and proline metabolism
hsa00340  Histidine metabolism
hsa00350  Tyrosine metabolism
hsa00360  Phenylalanine metabolism
hsa00380  Tryptophan metabolism
hsa00982  Drug metabolism - cytochrome P450
hsa04726  Serotonergic synapse
hsa04728  Dopaminergic synapse  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 N NERVOUS SYSTEM
  N06 PSYCHOANALEPTICS
   N06A ANTIDEPRESSANTS
    N06AF Monoamine oxidase inhibitors, non-selective
     N06AF02 Nialamide
      D07337  Nialamide (INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   monoamine oxidase (MAO)
    Nialamide
     D07337  Nialamide (NF/INN/BAN)
BRITE hierarchy
Other DBs
CAS: 
51-12-7
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        22
            1   C8x C    15.1900  -19.6700
            2   N5x N    15.1900  -21.0700
            3   C8x C    16.4024  -21.7700
            4   C8x C    17.6149  -21.0700
            5   C8y C    17.6149  -19.6700
            6   C8x C    16.4024  -18.9700
            7   C5a C    18.8524  -18.9700
            8   N1b N    20.0649  -19.6700
            9   N1b N    21.2773  -18.9700
            10  C1b C    22.4897  -19.6700
            11  C1b C    23.7022  -18.9700
            12  C5a C    24.9146  -19.6700
            13  N1b N    26.1270  -18.9700
            14  C1b C    27.3395  -19.6700
            15  C8y C    28.5519  -18.9700
            16  C8x C    29.7704  -19.6735
            17  C8x C    30.9828  -18.9735
            18  C8x C    30.9829  -17.5735
            19  C8x C    29.7644  -16.8700
            20  C8x C    28.5519  -17.5700
            21  O5a O    18.8586  -17.5703
            22  O5a O    24.9146  -21.0700
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     5   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   13  14 1
            15   14  15 1
            16   15  16 2
            17   16  17 1
            18   17  18 2
            19   18  19 1
            20   19  20 2
            21   15  20 1
            22    7  21 2
            23   12  22 2

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