KEGG   DRUG: D07377Help
Entry
D07377                      Drug                                   

Name
Bambuterol (INN)
Formula
C18H29N3O5
Exact mass
367.2107
Mol weight
367.44
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antiasthmatic;
beta2-Sympathomimetic agent
Remark
ATC code: 
Drug group: 
Comment
long-acting beta-adrenoceptor agonist (LABA)
prodrug, active substance: Terbutaline [DR:D08570]
Target
beta2-adrenergic receptor agonist [HSA:154] [KO:K04142]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04144  Endocytosis
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
   R03C ADRENERGICS FOR SYSTEMIC USE
    R03CC Selective beta-2-adrenoreceptor agonists
     R03CC12 Bambuterol
      D07377  Bambuterol (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    beta2-adrenergic receptor
     Bambuterol
      D07377  Bambuterol (INN)
BRITE hierarchy
Other DBs
CAS: 
81732-65-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8x C    16.8331  -16.5489
            2   C8y C    16.8331  -17.9514
            3   C8x C    18.0477  -18.6527
            4   C8y C    19.2625  -17.9514
            5   C8x C    19.2625  -16.5489
            6   C8y C    18.0477  -15.8476
            7   C1c C    20.5023  -18.6527
            8   C1b C    21.7170  -17.9514
            9   N1b N    22.9316  -18.6527
            10  O7a O    15.6185  -18.6527
            11  C7a C    14.4037  -17.9514
            12  N1c N    13.1891  -18.6527
            13  C1a C    11.9745  -17.9514
            14  O6a O    14.4037  -16.5491
            15  C1a C    13.1891  -20.0553
            16  O1a O    20.5085  -20.0550
            17  O7a O    18.0477  -14.4452
            18  C7a C    16.8163  -13.7341
            19  N1c N    15.6102  -14.4304
            20  C1a C    14.4249  -13.7460
            21  C1a C    15.6096  -15.7771
            22  O6a O    16.8165  -12.3412
            23  C1d C    24.1797  -17.9327
            24  C1a C    25.3641  -18.6171
            25  C1a C    24.1804  -16.5203
            26  C1a C    25.3921  -17.2327
BOND        26
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    2  10 1
            11   10  11 1
            12   11  12 1
            13   12  13 1
            14   11  14 2
            15   12  15 1
            16    7  16 1
            17    6  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 1
            21   19  21 1
            22   18  22 2
            23    9  23 1
            24   23  24 1
            25   23  25 1
            26   23  26 1

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