| Entry |
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| Name |
Pimethixene (INN);
Calmixene (TN)
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| Formula |
C19H19NS
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| Exact mass |
293.1238
|
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| Mol weight |
293.4259
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| Structure |
     |
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| Activity |
Histamine, H1-receptor antagonist
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| Remark |
|
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| Target |
|
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Interaction |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AX Other antihistamines for systemic use
R06AX23 Pimethixene
D07406 Pimethixene (INN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
muscarinic cholinergic receptor [HSA:1128 1129 1131 1132 1133] [KO:K04129 K04130 K04131 K04132 K04133]
Pimethixene [ATC:R06AX23]
D07406 Pimethixene (INN)
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| Other DBs |
CAS: 314-03-4 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 21
1 C8x C 15.7500 -18.9700
2 C8x C 15.7500 -20.3700
3 C8x C 16.9624 -21.0700
4 C8y C 18.1749 -20.3700
5 C8y C 18.1749 -18.9700
6 C8x C 16.9624 -18.2700
7 S2x S 19.3873 -21.0700
8 C8y C 20.5997 -20.3700
9 C8y C 20.5997 -18.9700
10 C8y C 19.3873 -18.2700
11 C8x C 21.8122 -21.0700
12 C8x C 23.0246 -20.3700
13 C8x C 23.0246 -18.9700
14 C8x C 21.8122 -18.2700
15 C2y C 19.3873 -16.8700
16 C1x C 20.6018 -16.1688
17 C1x C 20.6018 -14.7688
18 N1y N 19.3893 -14.0688
19 C1x C 18.1749 -14.7700
20 C1x C 18.1749 -16.1700
21 C1a C 19.3893 -12.6700
BOND 24
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 8 11 2
13 11 12 1
14 12 13 2
15 13 14 1
16 9 14 2
17 10 15 2
18 15 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
23 15 20 1
24 18 21 1
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