KEGG   DRUG: D07406Help
Entry
D07406                      Drug                                   

Name
Pimethixene (INN);
Calmixene (TN)
Formula
C19H19NS
Exact mass
293.1238
Mol weight
293.4259
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Histamine, H1-receptor antagonist
Remark
ATC code: 
Drug group: 
Target
H1-receptor antagonist [HSA:3269] [KO:K04149]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 R RESPIRATORY SYSTEM
  R06 ANTIHISTAMINES FOR SYSTEMIC USE
   R06A ANTIHISTAMINES FOR SYSTEMIC USE
    R06AX Other antihistamines for systemic use
     R06AX23 Pimethixene
      D07406  Pimethixene (INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Acetylcholine (muscarinic)
    muscarinic cholinergic receptor
     Pimethixene
      D07406  Pimethixene (INN)
BRITE hierarchy
Other DBs
CAS: 
314-03-4
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        21
            1   C8x C    15.7500  -18.9700
            2   C8x C    15.7500  -20.3700
            3   C8x C    16.9624  -21.0700
            4   C8y C    18.1749  -20.3700
            5   C8y C    18.1749  -18.9700
            6   C8x C    16.9624  -18.2700
            7   S2x S    19.3873  -21.0700
            8   C8y C    20.5997  -20.3700
            9   C8y C    20.5997  -18.9700
            10  C8y C    19.3873  -18.2700
            11  C8x C    21.8122  -21.0700
            12  C8x C    23.0246  -20.3700
            13  C8x C    23.0246  -18.9700
            14  C8x C    21.8122  -18.2700
            15  C2y C    19.3873  -16.8700
            16  C1x C    20.6018  -16.1688
            17  C1x C    20.6018  -14.7688
            18  N1y N    19.3893  -14.0688
            19  C1x C    18.1749  -14.7700
            20  C1x C    18.1749  -16.1700
            21  C1a C    19.3893  -12.6700
BOND        24
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12    8  11 2
            13   11  12 1
            14   12  13 2
            15   13  14 1
            16    9  14 2
            17   10  15 2
            18   15  16 1
            19   16  17 1
            20   17  18 1
            21   18  19 1
            22   19  20 1
            23   15  20 1
            24   18  21 1

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