KEGG   DRUG: BunaftineHelp
Entry
D07428                      Drug                                   

Name
Bunaftine (INN)
Formula
C21H30N2O
Exact mass
326.2358
Mol weight
326.4757
Structure
Mol fileKCF fileDB searchJmolKegDraw
Class
Cardiovascular agent
 DG01653  Antiarrhythmics
  DG01648  Class III antiarrhythmic agent
Remark
ATC code: 
Target
voltage-gated potassium channel;
voltage-gated sodium channel (SCN1A) [HSA:6323] [KO:K04833];
voltage-gated sodium channel (SCN2A) [HSA:6326] [KO:K04834];
voltage-gated sodium channel (SCN3A) [HSA:6328] [KO:K04836];
voltage-gated sodium channel (SCN4A) [HSA:6329] [KO:K04837];
voltage-gated sodium channel (SCN5A) [HSA:6331] [KO:K04838];
voltage-gated sodium channel (SCN8A) [HSA:6334] [KO:K04840];
voltage-gated sodium channel (SCN9A) [HSA:6335] [KO:K04841]
Interaction
Drug interaction
Structure map
Potassium channel blocking and opening drugs
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 C CARDIOVASCULAR SYSTEM
  C01 CARDIAC THERAPY
   C01B ANTIARRHYTHMICS, CLASS I AND III
    C01BD Antiarrhythmics, class III
     C01BD03 Bunaftine
      D07428  Bunaftine (INN)
BRITE hierarchy
Other DBs
CAS: 
32421-46-8
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        24
            1   C8x C    16.0300  -18.6900
            2   C8x C    16.0300  -20.0900
            3   C8x C    17.2424  -20.7900
            4   C8y C    18.4549  -20.0900
            5   C8y C    18.4549  -18.6900
            6   C8x C    17.2424  -17.9900
            7   C8x C    19.6673  -20.7900
            8   C8x C    20.8797  -20.0900
            9   C8x C    20.8797  -18.6900
            10  C8y C    19.6673  -17.9900
            11  C5a C    19.6673  -16.5900
            12  N1c N    20.8818  -15.8888
            13  O5a O    18.4569  -15.8912
            14  C1b C    22.0783  -16.5798
            15  C1b C    20.8818  -14.4902
            16  C1b C    22.0779  -13.7995
            17  C1b C    23.2653  -14.4851
            18  C1a C    24.4565  -13.7972
            19  C1b C    23.2651  -15.8946
            20  N1c N    24.4566  -16.5828
            21  C1b C    25.6460  -15.8961
            22  C1b C    24.4566  -17.9897
            23  C1a C    26.8362  -16.5835
            24  C1a C    25.6490  -18.6784
BOND        25
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 2
            9     8   9 1
            10    9  10 2
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   11  13 2
            15   12  14 1
            16   12  15 1
            17   15  16 1
            18   16  17 1
            19   17  18 1
            20   14  19 1
            21   19  20 1
            22   20  21 1
            23   20  22 1
            24   21  23 1
            25   22  24 1

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