KEGG   DRUG: D07451Help
Entry
D07451                      Drug                                   

Name
Amosulalol (INN)
Formula
C18H24N2O5S
Exact mass
380.1406
Mol weight
380.4586
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Antihypertansive;
alfa-Adrenergic blocking;
beta-Adrenergic blocking
Remark
Drug group: 
Target
alpha1-adrenergic receptor antagonist [HSA:146 147 148] [KO:K04137 K04136 K04135];
beta1-adrenergic receptor antagonist [HSA:153] [KO:K04141];
beta2-adrenergic receptor antagonist [HSA:154] [KO:K04142];
beta3-adrenergic receptor antagonist [HSA:155] [KO:K04143]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04270  Vascular smooth muscle contraction
hsa04970  Salivary secretion  
 
Interaction
Drug interaction
Structure map
beta-Adrenergic receptor agonists/antagonists
alpha-Adrenergic receptor agonists/antagonists
Brite
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    alpha1-adrenergic receptor
     Amosulalol
      D07451  Amosulalol (INN)
    beta1-adrenergic receptor
     Amosulalol
      D07451  Amosulalol (INN)
    beta2-adrenergic receptor
     Amosulalol
      D07451  Amosulalol (INN)
    beta3-adrenergic receptor
     Amosulalol
      D07451  Amosulalol (INN)
BRITE hierarchy
Other DBs
CAS: 
85320-68-9
PubChem: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        26
            1   C8y C    18.1300  -17.5700
            2   C8x C    18.1300  -18.9700
            3   C8x C    19.3900  -19.6700
            4   C8y C    20.5800  -18.9700
            5   C8x C    20.5800  -17.5700
            6   C8y C    19.3900  -16.8700
            7   C1a C    16.9400  -16.8700
            8   S4a S    19.3900  -15.4700
            9   N1a N    19.3900  -14.0700
            10  O3c O    17.9200  -15.4700
            11  O3c O    20.7200  -15.4700
            12  C1c C    21.8400  -19.6700
            13  C1b C    23.0300  -18.9700
            14  O1a O    21.8400  -21.0700
            15  N1b N    24.2200  -19.6700
            16  C1b C    25.4100  -18.9700
            17  C1b C    26.6000  -19.6700
            18  O2a O    27.7900  -18.9700
            19  C8y C    28.9800  -19.6700
            20  C8y C    28.9800  -21.0700
            21  C8x C    30.2400  -21.7700
            22  C8x C    31.4300  -21.0700
            23  C8x C    31.4300  -19.6700
            24  C8x C    30.2400  -18.9700
            25  O2a O    27.7900  -21.8400
            26  C1a C    26.5300  -21.1400
BOND        27
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     1   7 1
            8     6   8 1
            9     8   9 1
            10    8  10 2
            11    8  11 2
            12    4  12 1
            13   12  13 1
            14   12  14 1
            15   13  15 1
            16   15  16 1
            17   16  17 1
            18   17  18 1
            19   18  19 1
            20   19  20 2
            21   20  21 1
            22   21  22 2
            23   22  23 1
            24   23  24 2
            25   19  24 1
            26   20  25 1
            27   25  26 1

» Japanese version   » Back

DBGET integrated database retrieval system