| Entry |
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| Name |
Antazoline hydrochloride;
Phenazolinum (TN)
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| Formula |
C17H19N3. HCl
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| Exact mass |
301.1346
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| Mol weight |
301.8138
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| Structure |
     |
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| Activity |
Histamine, H1-receptor antagonist
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| Remark |
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| Target |
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| Pathway |
hsa04020 Calcium signaling pathway
hsa04080 Neuroactive ligand-receptor interaction | |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R01 NASAL PREPARATIONS
R01A DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
R01AC Antiallergic agents, excl. corticosteroids
R01AC04 Antazoline
D07459 Antazoline hydrochloride
R06 ANTIHISTAMINES FOR SYSTEMIC USE
R06A ANTIHISTAMINES FOR SYSTEMIC USE
R06AX Other antihistamines for systemic use
R06AX05 Antazoline
D07459 Antazoline hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Histamine
H1-receptor [HSA:3269] [KO:K04149]
Antazoline [ATC:R01AC04 R06AX05]
D07459 Antazoline hydrochloride
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| Other DBs |
CAS: 2508-72-7 PubChem: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 21
1 X Cl 33.3764 -18.1025
2 C8y C 24.0100 -17.4300
3 C8x C 24.0100 -18.7600
4 C8x C 25.2000 -19.4600
5 C8y C 26.4600 -18.7600
6 N1c N 26.4600 -17.4300
7 C1b C 25.2000 -16.7300
8 C8x C 27.6500 -19.4600
9 N2x N 28.8400 -18.7600
10 C2y C 28.8400 -17.4300
11 C1b C 27.6500 -16.7300
12 C8x C 22.8200 -16.7300
13 C8x C 21.5600 -17.4300
14 C8x C 21.5600 -18.7600
15 C8x C 22.8200 -19.4600
16 C8x C 25.2000 -20.8600
17 C8x C 26.4600 -21.5600
18 C8x C 27.6500 -20.8600
19 C1x C 30.1700 -19.1800
20 C1x C 31.0100 -18.1300
21 N1x N 30.1700 -17.0100
BOND 22
1 2 3 1
2 4 5 1
3 5 6 1
4 6 7 1
5 2 7 1
6 5 8 2
7 9 10 2
8 10 11 1
9 6 11 1
10 2 12 2
11 12 13 1
12 13 14 2
13 14 15 1
14 15 3 2
15 4 16 2
16 16 17 1
17 17 18 2
18 18 8 1
19 9 19 1
20 19 20 1
21 20 21 1
22 10 21 1
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