KEGG   DRUG: D07460Help
Entry
D07460                      Drug                                   

Name
Apomorphine (BAN);
Uprima (TN)
Formula
C17H17NO2
Exact mass
267.1259
Mol weight
267.3224
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Emetic;
Dopamine agonist;
Impotency agent
Remark
ATC code: 
Drug group: 
Comment
Morphine [DR:D08233] decomposition
Target
dopamine D1-receptor agonist [HSA:1812] [KO:K04144];
dopamine D2-receptor agonist [HSA:1813] [KO:K04145]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04540  Gap junction  
 
Interaction
Drug interaction
Structure map
Antiparkinsonian agents
Dopamine receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G04 UROLOGICALS
   G04B UROLOGICALS
    G04BE Drugs used in erectile dysfunction
     G04BE07 Apomorphine
      D07460  Apomorphine (BAN)
 N NERVOUS SYSTEM
  N04 ANTI-PARKINSON DRUGS
   N04B DOPAMINERGIC AGENTS
    N04BC Dopamine agonists
     N04BC07 Apomorphine
      D07460  Apomorphine (BAN)
USP drug classification [BR:br08302]
 Antiparkinson Agents
  Dopamine Agonists
   Apomorphine
    D07460  Apomorphine (BAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    dopamine D1-receptor
     Apomorphine
      D07460  Apomorphine (BAN)
    dopamine D2-receptor
     Apomorphine
      D07460  Apomorphine (BAN)
Phytochemicals used as drugs [BR:br08306]
 Alkaloids
  Alkaloids derived from tyrosine
   Isoquinoline alkaloids
    D07460  Apomorphine (BAN)
BRITE hierarchy
Other DBs
CAS: 
58-00-4
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        20
            1   C8x C    22.6800  -17.4300
            2   C8x C    22.6800  -18.8300
            3   C8x C    23.8924  -19.5300
            4   C8y C    25.1049  -18.8300
            5   C8y C    25.1049  -17.4300
            6   C8y C    23.8924  -16.7300
            7   C1x C    26.3173  -19.5300
            8   C1x C    27.5297  -18.8300
            9   N1y N    27.5297  -17.4300
            10  C1y C    26.3173  -16.7300
            11  C1x C    26.3173  -15.3300
            12  C8y C    25.1048  -14.6300
            13  C8y C    23.8924  -15.3300
            14  C8x C    25.1048  -13.2300
            15  C8x C    23.8923  -12.5300
            16  C8y C    22.6799  -13.2300
            17  C8y C    22.6799  -14.6300
            18  C1a C    28.7273  -16.7385
            19  O1a O    21.4675  -12.5301
            20  O1a O    21.4676  -15.3300
BOND        23
            1     1   2 2
            2     2   3 1
            3     3   4 2
            4     4   5 1
            5     5   6 2
            6     1   6 1
            7     4   7 1
            8     7   8 1
            9     8   9 1
            10    9  10 1
            11    5  10 1
            12   10  11 1
            13   11  12 1
            14   12  13 2
            15    6  13 1
            16   12  14 1
            17   14  15 2
            18   15  16 1
            19   16  17 2
            20   13  17 1
            21    9  18 1
            22   16  19 1
            23   17  20 1

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